Exerkines and Myokines in the Context of Muscle Aging

Source https://www.fightaging.org/archives/2025/08/exerkines-and-myokines-in-the-context-of-muscle-aging/

Muscle tissue is metabolically active and does produce effects on the rest of the body via signaling. Myokines are signal molecules produced my muscle tissue, while exerkines are signal molecules produced during exercise, and which induce improvements in tissue function, both in muscle and in other organs. This signaling is incompletely mapped and its effects in detail are not well understood outside of a few specific signals that have attracted research attention in past years. The broader topic of how muscle, and muscle use in exercise, influences function in the rest of the body is an area of interest for ongoing research. Researchers would like to produce exercise mimetic drugs, for example, analogous to cal…