Cells become senescent in response to damage, signaling of other senescent cells, or on reaching the Hayflick limit to cell replication. Senescent cells cease to replicate, secrete a potent mix of inflammatory signals, and near all self-destruct or are destroyed by the immune system. Unfortunately, some escape this fate, and so senescent cells accumulate with age to cause chronic inflammation, tissue remodeling, and age-related disease. A few years ago, researchers discovered a way to <a href="https://www.fight…
Cells become senescent in response to damage, signaling of other senescent cells, or on reaching the Hayflick limit to cell replication. Senescent cells cease to replicate, secrete a potent mix of inflammatory signals, and near all self-destruct or are destroyed by the immune system. Unfortunately, some escape this fate, and so senescent cells accumulate with age to cause chronic inflammation, tissue remodeling, and age-related disease. A few years ago, researchers discovered a way to <a href="https://www.fight…
The practice of calorie restriction is well documented to slow the progression of aging in mammals. In humans, there is comprehensive evidence for it to improve measures of health and reduce the risk of age-related disease. The mechanisms by which calorie restriction produces benefits are essentially the same across species, an upregulation of various stress response mechanisms that maintain and repair cell function. The short-term health benefits, the specific outcomes resulting from this favorable alteration in the operation of cellular metabolism, are also very similar. However, the extension of life span produced by calorie restriction diminishes as species life span increases. Calorie restriction can extend life in mice by up to 40%, but is thought to <a href="https://www.fightaging.org/archives/2005/08/michael-rose-on-calorie-restri…
The practice of calorie restriction is well documented to slow the progression of aging in mammals. In humans, there is comprehensive evidence for it to improve measures of health and reduce the risk of age-related disease. The mechanisms by which calorie restriction produces benefits are essentially the same across species, an upregulation of various stress response mechanisms that maintain and repair cell function. The short-term health benefits, the specific outcomes resulting from this favorable alteration in the operation of cellular metabolism, are also very similar. However, the extension of life span produced by calorie restriction diminishes as species life span increases. Calorie restriction can extend life in mice by up to 40%, but is thought to <a href="https://www.fightaging.org/archives/2005/08/michael-rose-on-calorie-restri…
So it’s time to exercise, but you’re confined to a small space?
No problem!
In our Online Coaching Program, where I’m a senior coach, we help folks work out in whatever nook and cranny they may have available. Today, we’ll share these tips with you too.
So it’s time to exercise, but you’re confined to a small space?
No problem!
In our Online Coaching Program, where I’m a senior coach, we help folks work out in whatever nook and cranny they may have available. Today, we’ll share these tips with you too.
November revealed a growing sense of urgency about older adults. What has been the impact on them of the daily onslaught of Covid-19 statistics? What about nine months of ceaseless updates about case counts? Has this produced a permanent fear of contact with others, including families, especially on holidays? Public-private partnerships are forming to bring devices and products to older adults, now isolated for as much as 9 months. Will that he…
November revealed a growing sense of urgency about older adults. What has been the impact on them of the daily onslaught of Covid-19 statistics? What about nine months of ceaseless updates about case counts? Has this produced a permanent fear of contact with others, including families, especially on holidays? Public-private partnerships are forming to bring devices and products to older adults, now isolated for as much as 9 months. Will that he…
Many a celeb has complained about cellulite (we’re lookin’ at you Kim K), giving this totally normal part of skin an unnecessary bad rap.
But, while cellulite is super common and nothing to worry about, lots of folks just don’t like having dimply skin. If you’re looking to ditch your cellulite, here are the best, proven ways to get rid of your cellulite, or at least diminish its appearance.
Marc Bordons/Stocksy United
What is cellulite anyway?
Cellulite happens when fat in the skin pushes up against connective tissue. This creates that uneven, bu…
Many a celeb has complained about cellulite (we’re lookin’ at you Kim K), giving this totally normal part of skin an unnecessary bad rap.
But, while cellulite is super common and nothing to worry about, lots of folks just don’t like having dimply skin. If you’re looking to ditch your cellulite, here are the best, proven ways to get rid of your cellulite, or at least diminish its appearance.
Marc Bordons/Stocksy United
What is cellulite anyway?
Cellulite happens when fat in the skin pushes up against connective tissue. This creates that uneven, bu…
Several research groups and companies are working on in vivo applications of cellular reprogramming. Today’s research materials cover recent work from David Sinclair’s team showing off the use of reprogramming to produce regeneration of damaged nervous system tissue in the eye and optic nerve. Glaucoma is a condition in which rising pressure in the eyeball progressively harms the retina and optic nerve. Since nerve tissue doesn’t regenerate well in mammals, loss of vision is irreversible. This is one of many conditions for which the ability to regenerate nerve tissue would be a great benefit.
…
Several research groups and companies are working on in vivo applications of cellular reprogramming. Today’s research materials cover recent work from David Sinclair’s team showing off the use of reprogramming to produce regeneration of damaged nervous system tissue in the eye and optic nerve. Glaucoma is a condition in which rising pressure in the eyeball progressively harms the retina and optic nerve. Since nerve tissue doesn’t regenerate well in mammals, loss of vision is irreversible. This is one of many conditions for which the ability to regenerate nerve tissue would be a great benefit.
…
“I have no special talent. I am only passionately curious.” ~Albert Einstein
When speaking to a parent recently, she said, “I have made it a rule that my kids read every day for an hour. There are no two ways about it. They now do it and it is great, but I have noticed that they have stopped asking questions, they have stopped being curious, and they look dull, and that bothers me.”
Strange that reading would dull their curiosity instead of sparking it. But beyond that, this conversation got me curious—about curiosity.
Why is it important to be curious? And is it even possible to stop being curious?
Do you remember when you were a child, just grabbing anything and everything and looking at it from all angles, exploring what it was?
“I have no special talent. I am only passionately curious.” ~Albert Einstein
When speaking to a parent recently, she said, “I have made it a rule that my kids read every day for an hour. There are no two ways about it. They now do it and it is great, but I have noticed that they have stopped asking questions, they have stopped being curious, and they look dull, and that bothers me.”
Strange that reading would dull their curiosity instead of sparking it. But beyond that, this conversation got me curious—about curiosity.
Why is it important to be curious? And is it even possible to stop being curious?
Do you remember when you were a child, just grabbing anything and everything and looking at it from all angles, exploring what it was?
November revealed a growing sense of urgency about older adults. What has been the impact on them of the daily onslaught of Covid-19 statistics? What about nine months of ceaseless updates about case counts? Has this produced a permanent fear of contact with others, including families, 
