Source https://minimalistbaker.com/chocolate-pecan-shortbread-cookies-vegan-gf/
Say hello to crispy, buttery shortbread cookies studded with pecans and dark chocolate (swoon!). These cookies are our vegan and gluten-free twist on Alison Roman’s legendary Salted Chocolate Chunk Shortbread Cookies and (just like Alison’s), they’re too good to eat just one!
Just 7 ingredients and simple methods stand in your way. Grab your mixing bowl and let’s bake, friends!
Chocolate Pecan Shortb…
Source https://minimalistbaker.com/chocolate-pecan-shortbread-cookies-vegan-gf/
Say hello to crispy, buttery shortbread cookies studded with pecans and dark chocolate (swoon!). These cookies are our vegan and gluten-free twist on Alison Roman’s legendary Salted Chocolate Chunk Shortbread Cookies and (just like Alison’s), they’re too good to eat just one!
Just 7 ingredients and simple methods stand in your way. Grab your mixing bowl and let’s bake, friends!
Chocolate Pecan Shortb…
Source https://www.fightaging.org/archives/2024/12/is-brain-volume-loss-following-anti-amyloid-therapy-actually-a-bad-thing/
That loss of brain volume is a bad thing, resulting from the loss of necessary cells, is a concept central to the research and clinical fields. It occurs in the late stages of Alzheimer’s disease as cells die and cognitive function is lost. So it is interesting to see this view challenged in the context of the recently approved amyloid-clearing immunotherapies. Is brain volume loss following treatment a function of mechanisms other than loss of cells? Is it actually a beneficial outcome? I can see it requiring a great deal more time, funding, and data to convince the broader field that this is the case.
Researchers analysed data from a dozen different trials of amyloid-targeting immunotherapy. While brain shrinkage is usually an undesirable outcome, the team found that the exce…
Source https://www.fightaging.org/archives/2024/12/is-brain-volume-loss-following-anti-amyloid-therapy-actually-a-bad-thing/
That loss of brain volume is a bad thing, resulting from the loss of necessary cells, is a concept central to the research and clinical fields. It occurs in the late stages of Alzheimer’s disease as cells die and cognitive function is lost. So it is interesting to see this view challenged in the context of the recently approved amyloid-clearing immunotherapies. Is brain volume loss following treatment a function of mechanisms other than loss of cells? Is it actually a beneficial outcome? I can see it requiring a great deal more time, funding, and data to convince the broader field that this is the case.
Researchers analysed data from a dozen different trials of amyloid-targeting immunotherapy. While brain shrinkage is usually an undesirable outcome, the team found that the exce…
Source https://www.fightaging.org/archives/2024/12/a-growing-population-of-harmful-megakaryocyte-progenitors-contribute-to-age-related-thrombosis/
Blood clotting relies upon platelets and the reaction of those platelets to circumstances that indicate clotting is required: when suitably provoked platelets adhere to tissue, change shape, and bind to one another to form a clot. Platelets are essentially small slices of cell membrane and cytoplasm, shed by a specialized form of bone marrow cell called a megakaryocyte. Like all complex processes, clotting is impacted by age-related changes in cells and tissue. Platelets become more willing to clot, and can produce inappropriate clotting inside blood vessels, leading to thrombosis. We might ask how much of this problem is innate to platelets versus aris…
Source https://www.fightaging.org/archives/2024/12/a-growing-population-of-harmful-megakaryocyte-progenitors-contribute-to-age-related-thrombosis/
Blood clotting relies upon platelets and the reaction of those platelets to circumstances that indicate clotting is required: when suitably provoked platelets adhere to tissue, change shape, and bind to one another to form a clot. Platelets are essentially small slices of cell membrane and cytoplasm, shed by a specialized form of bone marrow cell called a megakaryocyte. Like all complex processes, clotting is impacted by age-related changes in cells and tissue. Platelets become more willing to clot, and can produce inappropriate clotting inside blood vessels, leading to thrombosis. We might ask how much of this problem is innate to platelets versus aris…
Source https://tinybuddha.com/blog/from-pain-to-power-letting-go-of-approval-to-love-myself/
“If you love yourself, it doesn’t matter if other people like you because you don’t need their approval to feel good about yourself.” ~Lori Deschene
For most of my life, I worried about what others thought. Every move I made felt like a performance for someone else. I’d built my life on their approval.
Then came the losses. Three family members were gone in a matter of years. Each time, the grief hit like a fist to the gut.
My mother was my pillar of strength; my father, who might not have always been there for me but was still my father, went next, and then my younger brother—a cruel fate.
Their absence left a void that seemed impossible to fill.
I felt hollow, like someone had punched all the air out of me. I was left winded and empty. Grief, relentless and heavy, k…
Source https://tinybuddha.com/blog/from-pain-to-power-letting-go-of-approval-to-love-myself/
“If you love yourself, it doesn’t matter if other people like you because you don’t need their approval to feel good about yourself.” ~Lori Deschene
For most of my life, I worried about what others thought. Every move I made felt like a performance for someone else. I’d built my life on their approval.
Then came the losses. Three family members were gone in a matter of years. Each time, the grief hit like a fist to the gut.
My mother was my pillar of strength; my father, who might not have always been there for me but was still my father, went next, and then my younger brother—a cruel fate.
Their absence left a void that seemed impossible to fill.
I felt hollow, like someone had punched all the air out of me. I was left winded and empty. Grief, relentless and heavy, k…
Source https://www.fightaging.org/archives/2024/12/mapping-transcriptional-changes-produced-by-intermittent-fasting-and-the-fasting-mimicking-diet/
Forms of fasting and calorie restriction all function to produce sweeping, favorable alterations to metabolism. In short-lived animals, these changes significantly extend healthy life span. In long-lived animals, the effects on life span are more muted. The challenge in understanding the interaction between reduced calorie intake and pace of aging is that near everything changes in response to diet. There is no firm understanding at the detail level to link the copious observations into a coherent explanation of how aging is slowed. While evidence points to upregulation of autophagy as the primary mechanism connecting reduced calorie intake…
Source https://www.fightaging.org/archives/2024/12/mapping-transcriptional-changes-produced-by-intermittent-fasting-and-the-fasting-mimicking-diet/
Forms of fasting and calorie restriction all function to produce sweeping, favorable alterations to metabolism. In short-lived animals, these changes significantly extend healthy life span. In long-lived animals, the effects on life span are more muted. The challenge in understanding the interaction between reduced calorie intake and pace of aging is that near everything changes in response to diet. There is no firm understanding at the detail level to link the copious observations into a coherent explanation of how aging is slowed. While evidence points to upregulation of autophagy as the primary mechanism connecting reduced calorie intake…
Source https://www.theminimalists.com/p471/
By The Minimalists · Follow: Facebook, Instagram
The Minimalists dive deep into the anxiety that often accompanies the holiday shopping season.
Listen to the Episode
Apple · <a href="https://open.sp…
Source https://www.theminimalists.com/p471/
By The Minimalists · Follow: Facebook, Instagram
The Minimalists dive deep into the anxiety that often accompanies the holiday shopping season.
Listen to the Episode
Apple · <a href="https://open.sp…
The WSJ article circles the problem. When 41,000 older adults die as a result of falls each year at a cost of $80 billion (