It is never too late to start
Source https://seniorplanet.org/apps-for-that-summer-road-trip/
Savvy road trippers know that a smartphone is their best friend on the road – and there are more options besides Google Maps.
The post Apps for that Summer Road Trip appeared first on Senior Planet from AARP.
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Source https://seniorplanet.org/apps-for-that-summer-road-trip/
Savvy road trippers know that a smartphone is their best friend on the road – and there are more options besides Google Maps.
The post Apps for that Summer Road Trip appeared first on Senior Planet from AARP.
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The immune system becomes ever more inflammatory with advancing age, a state known as inflammaging, even as it loses competence in destroying pathogens and unwanted cells. This sustained, unresolved inflammation is harmful, the cause of numerous harmful changes in cell function and failures of tissue maintenance. It accelerates the onset and progression of all of the common age-related conditions. This is caused in part by the pro-inflammatory signaling of senescent cells, present in increasing numbers in the aged body. Another important contribution, and a focus in today’s open access paper, is the activation of <a h…
The immune system becomes ever more inflammatory with advancing age, a state known as inflammaging, even as it loses competence in destroying pathogens and unwanted cells. This sustained, unresolved inflammation is harmful, the cause of numerous harmful changes in cell function and failures of tissue maintenance. It accelerates the onset and progression of all of the common age-related conditions. This is caused in part by the pro-inflammatory signaling of senescent cells, present in increasing numbers in the aged body. Another important contribution, and a focus in today’s open access paper, is the activation of <a h…
As scientists note here, a number of reptilian and amphibian species exhibit negligible senescence, in that their mortality risk does not increase with age, at least not until very late life. The question has always been whether there is anything that can be learned from the cellular biochemistry of these species that can serve as the basis for enhancement therapies in mammals. There is no assurance that the basis of negligible senescence in any given species is simple enough to be useful. There is no assurance that even a simple difference could be safely ported over into mammalian biology given the biotechnology of the next few decades. Nonetheless, it is a topic of interest in the research community, a way to broaden the understanding of how differences in genetics and metabolism give rise to sizable differ…
As scientists note here, a number of reptilian and amphibian species exhibit negligible senescence, in that their mortality risk does not increase with age, at least not until very late life. The question has always been whether there is anything that can be learned from the cellular biochemistry of these species that can serve as the basis for enhancement therapies in mammals. There is no assurance that the basis of negligible senescence in any given species is simple enough to be useful. There is no assurance that even a simple difference could be safely ported over into mammalian biology given the biotechnology of the next few decades. Nonetheless, it is a topic of interest in the research community, a way to broaden the understanding of how differences in genetics and metabolism give rise to sizable differ…
Source https://seniorplanet.org/open-thread-shopping-sprees-and-retail-therapy/
Sometimes the simple things…aren’t so simple – like a shopping spree with a good friend. It’s really retail therapy. What do you buy that lifts you?
The post Open Thread: Shopping Sprees and Retail Therapy appeared first on Senior Planet from AARP.
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Source https://seniorplanet.org/open-thread-shopping-sprees-and-retail-therapy/
Sometimes the simple things…aren’t so simple – like a shopping spree with a good friend. It’s really retail therapy. What do you buy that lifts you?
The post Open Thread: Shopping Sprees and Retail Therapy appeared first on Senior Planet from AARP.
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Researchers here report on an investigation of mechanisms by which aged human skin is improved in function when transplanted onto young immunocompromised mice. They identified VEGF-A as a factor involved in this improvement, and showed that delivering VEGF-A to human skin models can reduce signatures of aging. This is interesting, as a number of skin conditions exhibit high levels of VEGF-A, and are treated by therapies that are shown to inhibit VEGF-A in addition to other effects. Thus more work is needed here in order to understand whether or not VEGF-A based treatments are a viable path to improving aged skin function.
Human skin is ideally suited as a preclinical aging research model but is rarely used by mainstream aging research for this purpose. Yet, aging …
Researchers here report on an investigation of mechanisms by which aged human skin is improved in function when transplanted onto young immunocompromised mice. They identified VEGF-A as a factor involved in this improvement, and showed that delivering VEGF-A to human skin models can reduce signatures of aging. This is interesting, as a number of skin conditions exhibit high levels of VEGF-A, and are treated by therapies that are shown to inhibit VEGF-A in addition to other effects. Thus more work is needed here in order to understand whether or not VEGF-A based treatments are a viable path to improving aged skin function.
Human skin is ideally suited as a preclinical aging research model but is rarely used by mainstream aging research for this purpose. Yet, aging …
Researchers here note a sizable reduction in Alzheimer’s disease risk in that part of the aged population that receives influenza vaccines. There is the usual question as to whether vaccination is a proxy for conscientiousness in health matters throughout later life, but here the focus is on biological mechanisms that might explain the effect. The most plausible to my eyes is the phenomenon of trained immunity, in which vaccination for a specific pathogen can provoke a general improvement in all functions of the innate immune system. This improvement includes reduced inflammation, and the <a href="https://www.fightaging…
Researchers here note a sizable reduction in Alzheimer’s disease risk in that part of the aged population that receives influenza vaccines. There is the usual question as to whether vaccination is a proxy for conscientiousness in health matters throughout later life, but here the focus is on biological mechanisms that might explain the effect. The most plausible to my eyes is the phenomenon of trained immunity, in which vaccination for a specific pathogen can provoke a general improvement in all functions of the innate immune system. This improvement includes reduced inflammation, and the <a href="https://www.fightaging…
Source https://www.fightaging.org/archives/2022/07/fight-aging-newsletter-july-4th-2022/
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out more: https://www.fightaging.org/services/
Contents
Source https://www.fightaging.org/archives/2022/07/fight-aging-newsletter-july-4th-2022/
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out more: https://www.fightaging.org/services/
Contents
Source https://zenhabits.net/create-life/
Very often, the way we live our lives is that we go through the motions — we do our work, try our best, tackle the things we have to do, take on our obligations, or we slack off on those obligations and find comforts where we can.
What we often forget is that no matter what, we’re creating our lives.
What if we took a more intentional approach, and created our lives on purpose?
What if we took life as a blank slate, and decided what we really wanted it to look like? What if we felt empowered to choose, to create, to bring to life what our hearts really wanted?
In this post, I’m going to share three questions to seriously take on, if you want to create your life.
I highly encourage you to take these on with full commitment. Pour yourself into them, don’t just read and think about them. Set time aside, go for a walk, take along a notebook, and r…
Source https://zenhabits.net/create-life/
Very often, the way we live our lives is that we go through the motions — we do our work, try our best, tackle the things we have to do, take on our obligations, or we slack off on those obligations and find comforts where we can.
What we often forget is that no matter what, we’re creating our lives.
What if we took a more intentional approach, and created our lives on purpose?
What if we took life as a blank slate, and decided what we really wanted it to look like? What if we felt empowered to choose, to create, to bring to life what our hearts really wanted?
In this post, I’m going to share three questions to seriously take on, if you want to create your life.
I highly encourage you to take these on with full commitment. Pour yourself into them, don’t just read and think about them. Set time aside, go for a walk, take along a notebook, and r…
Source https://greatist.com/fitness/kas-glute-bridge
Even if you’ve never done a standard glute bridge or barbell hip thrust, a Kas glute bridge is a simple variation that targets the right areas.
A standard glute bridge is a great exercise that works your hamstrings, quads, and, yes, glutes while stretching your hip flexors. However, you can also do many variations of it, from single-leg to incline, depending on your goals.
If you want a booty you can bounce a quarter off of, the Kas glute bridge is one variation you may want to start doing on the regular.
Why? This exercise takes your quads out of the equation and isolates your glutes as the main hip extensors with slow, controlled movement.
The difference between a glute bridge and a Kas glute bridge is subtle, but subtlety is where you get some shape in that ba-donk-a-donk.
<figure class="w…
Source https://greatist.com/fitness/kas-glute-bridge
Even if you’ve never done a standard glute bridge or barbell hip thrust, a Kas glute bridge is a simple variation that targets the right areas.
A standard glute bridge is a great exercise that works your hamstrings, quads, and, yes, glutes while stretching your hip flexors. However, you can also do many variations of it, from single-leg to incline, depending on your goals.
If you want a booty you can bounce a quarter off of, the Kas glute bridge is one variation you may want to start doing on the regular.
Why? This exercise takes your quads out of the equation and isolates your glutes as the main hip extensors with slow, controlled movement.
The difference between a glute bridge and a Kas glute bridge is subtle, but subtlety is where you get some shape in that ba-donk-a-donk.
<figure class="w…
Source https://greatist.com/discover/split-hair-dye
Split hair dye is a trendy hairstyle that involves splitting the hair down the middle and dyeing each half a different color. Think Cruella de Vil, but with color.
Split hair dye is when you dye half your head one color and the other half another.
Some peeps like to use standout colors like neon pink combined with a bold blue. Others prefer a softer look with combinations like peach and blonde or gray with black. But no matter what colors you chose, this hairstyle is fun, stylish, and cool AF.
Here’s a step-by-step guide on how to DIY split hair dye at home. We also have a rundown of popular split hairstyles and tips on preventing color bleeding.
Yep, it’s possible to split dye your hair at home! Just keep in mind that it can be a bit tough, especially if you’re…
Source https://greatist.com/discover/split-hair-dye
Split hair dye is a trendy hairstyle that involves splitting the hair down the middle and dyeing each half a different color. Think Cruella de Vil, but with color.
Split hair dye is when you dye half your head one color and the other half another.
Some peeps like to use standout colors like neon pink combined with a bold blue. Others prefer a softer look with combinations like peach and blonde or gray with black. But no matter what colors you chose, this hairstyle is fun, stylish, and cool AF.
Here’s a step-by-step guide on how to DIY split hair dye at home. We also have a rundown of popular split hairstyles and tips on preventing color bleeding.
Yep, it’s possible to split dye your hair at home! Just keep in mind that it can be a bit tough, especially if you’re…