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Prevalence of Cellular Senescence May Explain the Inverse Correlation Between Cancer and Neurodegeneration

Source https://www.fightaging.org/archives/2021/03/prevalence-of-cellular-senescence-may-explain-the-inverse-correlation-between-cancer-and-neurodegeneration/

One of the more curious aspects of aging is that risk of Alzheimer’s disease and risk of cancer is inversely correlated. Why is this the case? Researchers here suggest that cellular senescence may be an important component of this relationship. If cells in a given individual are more than averagely prone to becoming senescent in response to stress and damage, then this may lower the risk of cancer, as precancerous cells will be blocked from replication and removed by the immune system more efficiently. On the other hand, increased cellular senescence in the aging brain will more rapidly drive <a href="https://www.fightaging.org/archives/2016/08/considering-the-mechanisms-and-treatmen…

Source https://www.fightaging.org/archives/2021/03/prevalence-of-cellular-senescence-may-explain-the-inverse-correlation-between-cancer-and-neurodegeneration/

One of the more curious aspects of aging is that risk of Alzheimer’s disease and risk of cancer is inversely correlated. Why is this the case? Researchers here suggest that cellular senescence may be an important component of this relationship. If cells in a given individual are more than averagely prone to becoming senescent in response to stress and damage, then this may lower the risk of cancer, as precancerous cells will be blocked from replication and removed by the immune system more efficiently. On the other hand, increased cellular senescence in the aging brain will more rapidly drive <a href="https://www.fightaging.org/archives/2016/08/considering-the-mechanisms-and-treatmen…

The Minimalists on Clubhouse

Source https://www.theminimalists.com/clubhouse/

By Joshua Fields Millburn & Ryan Nicodemus ·

This Sunday, March 21, 2021, at 6 PM Pacific Time, The Minimalists are going to host our first Clubhouse room: Understanding Minimalism. Follow Josh…

Source https://www.theminimalists.com/clubhouse/

By Joshua Fields Millburn & Ryan Nicodemus ·

This Sunday, March 21, 2021, at 6 PM Pacific Time, The Minimalists are going to host our first Clubhouse room: Understanding Minimalism. Follow Josh…

The Signs of a Strong Friendship (and an Unhealthy One)

Source http://feedproxy.google.com/~r/tinybuddha/~3/rgScGM-apLs/

“Lots of people want to ride with you in the limo, but what you want is someone who will take the bus with you when the limo breaks down.” ~Oprah Winfrey

“How on earth am I supposed to survive? I have no friends whatsoever!”

These were the thoughts that ran through my mind then when I first set foot in London five years ago. I felt raw and vulnerable in the beautiful new city that I had to make my new home, alone, with my two kids, while my husband was overseas. I wondered how I was supposed to do it all.

Well, I had J, a friend I’d met on my honeymoon in Bali, but we had only kept in touch occasionally, so I didn’t expect much from her. I couldn’t really call her my friend, maybe a pleasant acquaintance, but surprisingly she turned out to b…

Source http://feedproxy.google.com/~r/tinybuddha/~3/rgScGM-apLs/

“Lots of people want to ride with you in the limo, but what you want is someone who will take the bus with you when the limo breaks down.” ~Oprah Winfrey

“How on earth am I supposed to survive? I have no friends whatsoever!”

These were the thoughts that ran through my mind then when I first set foot in London five years ago. I felt raw and vulnerable in the beautiful new city that I had to make my new home, alone, with my two kids, while my husband was overseas. I wondered how I was supposed to do it all.

Well, I had J, a friend I’d met on my honeymoon in Bali, but we had only kept in touch occasionally, so I didn’t expect much from her. I couldn’t really call her my friend, maybe a pleasant acquaintance, but surprisingly she turned out to b…

Ecore Introduces New Slip-Resistant Safety Floor HydroGrip Motivate Featuring its TRU Technology

Source https://www.clubindustry.com/press-releases/ecore-introduces-new-slip-resistant-safety-floor-hydrogrip-motivate-featuring-its

Ecore Introduces New Slip-Resistant Safety Floor HydroGrip Motivate Featuring its TRU Technology
tbeebe
Wed, 03/17/2021 – 19:57
<a class…

Source https://www.clubindustry.com/press-releases/ecore-introduces-new-slip-resistant-safety-floor-hydrogrip-motivate-featuring-its

Ecore Introduces New Slip-Resistant Safety Floor HydroGrip Motivate Featuring its TRU Technology
tbeebe
Wed, 03/17/2021 – 19:57
<a class…

Washington Sports Club Sued Again by DC Attorney General

Source https://www.clubindustry.com/commercial-clubs/washington-sports-club-sued-again-by-dc-attorney-general

Washington Sports Club Sued Again by DC Attorney General
pkufahl
Thu, 03/18/2021 – 12:08

Source https://www.clubindustry.com/commercial-clubs/washington-sports-club-sued-again-by-dc-attorney-general

Washington Sports Club Sued Again by DC Attorney General
pkufahl
Thu, 03/18/2021 – 12:08

Hearing aids, the elderly, and listening to music

Source https://www.ageinplacetech.com/blog/hearing-aids-elderly-and-listening-music

Hearing aids and music — why is this so difficult to solve for the elderly?  The pandemic isolated everyone, but it may have been even worse for the hearing-impaired. Consider the oldest — they are aged 85 or 86, love music and enjoy getting together with others in restaurants. The man loses one of the uninsured hearing aids and has to switch to backups that emit whistles or screeches, and cannot hear accurate sounds from a grand piano. The replacement cost of the single hearing aid is $2195 bundled with audiologist assistance. That pair worked well with his <a href="https://www.p…

Source https://www.ageinplacetech.com/blog/hearing-aids-elderly-and-listening-music

Hearing aids and music — why is this so difficult to solve for the elderly?  The pandemic isolated everyone, but it may have been even worse for the hearing-impaired. Consider the oldest — they are aged 85 or 86, love music and enjoy getting together with others in restaurants. The man loses one of the uninsured hearing aids and has to switch to backups that emit whistles or screeches, and cannot hear accurate sounds from a grand piano. The replacement cost of the single hearing aid is $2195 bundled with audiologist assistance. That pair worked well with his <a href="https://www.p…

How I Stopped Dismissing Praise and Started Believing Compliments

Source http://feedproxy.google.com/~r/tinybuddha/~3/mKsCAFy7DFY/

“I’ve met people who are embattled and dismissive, but when you get to know them, you find that they’re vulnerable—that hauteur or standoffishness is because they’re pedaling furiously underneath.” ~Matthew Macfadyen

It was impossible to miss the dismissive hand gesture and distasteful look on her face in response to my comment.

“You ooze empathy,” I had said in all sincerity to my therapist.

“And what’s it like if I blow off or disregard that compliment?” she countered. Then, as usual, she waited.

“Ah, it feels terrible,” I sputtered as the lights of insight began to flicker. I was acutely aware of an unpleasant feeling spreading throughout my chest and stomach. I sensed I had just deeply hurt someone’s feelings.

That experience hung in…

Source http://feedproxy.google.com/~r/tinybuddha/~3/mKsCAFy7DFY/

“I’ve met people who are embattled and dismissive, but when you get to know them, you find that they’re vulnerable—that hauteur or standoffishness is because they’re pedaling furiously underneath.” ~Matthew Macfadyen

It was impossible to miss the dismissive hand gesture and distasteful look on her face in response to my comment.

“You ooze empathy,” I had said in all sincerity to my therapist.

“And what’s it like if I blow off or disregard that compliment?” she countered. Then, as usual, she waited.

“Ah, it feels terrible,” I sputtered as the lights of insight began to flicker. I was acutely aware of an unpleasant feeling spreading throughout my chest and stomach. I sensed I had just deeply hurt someone’s feelings.

That experience hung in…

The Present Understanding of the Relationship Between Growth Hormone and Longevity

Source https://www.fightaging.org/archives/2021/03/the-present-understanding-of-the-relationship-between-growth-hormone-and-longevity/

Growth hormone treatments (and other hormone therapies) have a legitimate use in patients suffering excessively low hormone levels due to one or another cause. They have also long been overhyped and aggressively marketed by the anti-aging medicine community, not a field noted for its adherence to standards of truth and scientific accuracy. At the same time, the scientific evidence has consistently shown that <a href="https://www.fightaging.org/archives/2018/05/a-review-of-growth-hormone-in-aging/"<aging is accelerated by higher levels of growth hormone. Tall people exhibit a modestly greater degree of age-related disease and mortality, for example, while the longest-l…

Source https://www.fightaging.org/archives/2021/03/the-present-understanding-of-the-relationship-between-growth-hormone-and-longevity/

Growth hormone treatments (and other hormone therapies) have a legitimate use in patients suffering excessively low hormone levels due to one or another cause. They have also long been overhyped and aggressively marketed by the anti-aging medicine community, not a field noted for its adherence to standards of truth and scientific accuracy. At the same time, the scientific evidence has consistently shown that <a href="https://www.fightaging.org/archives/2018/05/a-review-of-growth-hormone-in-aging/"<aging is accelerated by higher levels of growth hormone. Tall people exhibit a modestly greater degree of age-related disease and mortality, for example, while the longest-l…

The Fear of Putting Our Work Out There

Source https://zenhabits.net/publishing/

By Leo Babauta

One of the most common fears of anyone who is creating something, whether it’s online content or art or a new business or startup … is the fear of putting our work out there in the world.

It’s a fear that has us procrastinating, researching endlessly, checking social media, answering emails, buying books on the topic, listening to podcasts and watching Youtube videos, cleaning our kitchen, deciding the laptop needs a good cleaning … endlessly!

None of these things are wrong or bad — they’re so human! But it’s a fear we have to face at some point if we ever want to make an impact on the world.

I’d love to share how I work with this fear — I’ve been doing it for decades now!

The brief summary:

  1. I have a litmus test: if I’m not creating or putting the creation out into the world, there’s a good chance I&#821…

Source https://zenhabits.net/publishing/

By Leo Babauta

One of the most common fears of anyone who is creating something, whether it’s online content or art or a new business or startup … is the fear of putting our work out there in the world.

It’s a fear that has us procrastinating, researching endlessly, checking social media, answering emails, buying books on the topic, listening to podcasts and watching Youtube videos, cleaning our kitchen, deciding the laptop needs a good cleaning … endlessly!

None of these things are wrong or bad — they’re so human! But it’s a fear we have to face at some point if we ever want to make an impact on the world.

I’d love to share how I work with this fear — I’ve been doing it for decades now!

The brief summary:

  1. I have a litmus test: if I’m not creating or putting the creation out into the world, there’s a good chance I&#821…

2 Self-Care Tips for Creating an Effective Sleep Plan

Source https://greatist.com/grow/self-care-building-a-sleep-plan

You’re here! That means it’s Monday, or it’s feeling like one. Don’t worry Greatist has your back. Subscribe to our newsletter for direct access to Mondays with Minaa, a mental health column by our resident self-care expert, Minaa.

mondays-with-minaa-self-care-tips
Design by Alexis Lira

Hi and happy Monday!

How was your quality of sleep over the past 7 days? Last week’s newsletter was about how Revenge Bedtime Procrastination emerged for many folks during the pandemic. As much as we might want to spend our nights reclaiming our personal time …

Source https://greatist.com/grow/self-care-building-a-sleep-plan

You’re here! That means it’s Monday, or it’s feeling like one. Don’t worry Greatist has your back. Subscribe to our newsletter for direct access to Mondays with Minaa, a mental health column by our resident self-care expert, Minaa.

mondays-with-minaa-self-care-tips
Design by Alexis Lira

Hi and happy Monday!

How was your quality of sleep over the past 7 days? Last week’s newsletter was about how Revenge Bedtime Procrastination emerged for many folks during the pandemic. As much as we might want to spend our nights reclaiming our personal time …

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