Angiotensin II Increases Oxidative Stress in Aging

Source https://www.fightaging.org/archives/2022/12/angiotensin-ii-increases-oxidative-stress-in-aging/

Researchers here suggest that angiotensin II expression is maladaptive in the context of aging, provoking greater oxidative stress and harmful downstream consequences for cell and tissue function. If looking to produce therapies based on interfering in angiotensin II receptor signaling, an approach already well established in the treatment of hypertension, the question is always the tradeoff between loss of function and avoidance of damage. Few if any molecular interactions in the body are entirely dispensable, and angiotensin II signaling is involved in a range of normal cellular processes. That said, this topic is well explored via the existing uses of ang…

Source https://www.fightaging.org/archives/2022/12/angiotensin-ii-increases-oxidative-stress-in-aging/

Researchers here suggest that angiotensin II expression is maladaptive in the context of aging, provoking greater oxidative stress and harmful downstream consequences for cell and tissue function. If looking to produce therapies based on interfering in angiotensin II receptor signaling, an approach already well established in the treatment of hypertension, the question is always the tradeoff between loss of function and avoidance of damage. Few if any molecular interactions in the body are entirely dispensable, and angiotensin II signaling is involved in a range of normal cellular processes. That said, this topic is well explored via the existing uses of ang…

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