Cellular Copper Requirements as a Target for Cancer Therapies

Source https://www.fightaging.org/archives/2024/11/cellular-copper-requirements-as-a-target-for-cancer-therapies/

In order to achieve meaningful progress in our lifetimes, the future of cancer therapy must become driven by a focus on common features that occur in all or near all cancers, and which are fundamental to the biology of cancer. Approaching the biochemistry of cancer in any other way leads to therapies that are only relevant to a small fraction of all cancers, targeting mechanisms that a tumor cell population is quite capable of evolving away from, given the selection pressure applied by the treatment. There are only so many researchers and only so much research funding. To find success in controlling cancer as a class of disease, future cancer therapies must have the potential to be very broadly applicable, to need minimal changes or no changes in delivery to target different forms of cancer.

Cancerous cells replicate rapidly. Biochemical differences in cancer cells that are an inevitable consequence of…

Source https://www.fightaging.org/archives/2024/11/cellular-copper-requirements-as-a-target-for-cancer-therapies/

In order to achieve meaningful progress in our lifetimes, the future of cancer therapy must become driven by a focus on common features that occur in all or near all cancers, and which are fundamental to the biology of cancer. Approaching the biochemistry of cancer in any other way leads to therapies that are only relevant to a small fraction of all cancers, targeting mechanisms that a tumor cell population is quite capable of evolving away from, given the selection pressure applied by the treatment. There are only so many researchers and only so much research funding. To find success in controlling cancer as a class of disease, future cancer therapies must have the potential to be very broadly applicable, to need minimal changes or no changes in delivery to target different forms of cancer.

Cancerous cells replicate rapidly. Biochemical differences in cancer cells that are an inevitable consequence of…

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