Cellular Senescence in Skin as an Early Sign of Aging

Source https://www.fightaging.org/archives/2023/05/cellular-senescence-in-skin-as-an-early-sign-of-aging/

While no-one likes to be reminded of it, there are clear, albeit minor signs of aging that arise in as young a stage of life as the late 20s and early 30s. These early manifestations of aging are very poorly understood; perhaps understandably, near all research into mechanisms of aging is focused on late life pathology and its causes. Thus we are left with a very unsatisfactory understanding of what exactly is going in early adult life that makes a mid-30s adult physiologically different from an immediately post-development teenager.

In today’s open access commentary, researchers report on evidence implicating senescent cells in these differences, at least in skin, and this is quite interesting. Present understanding holds that the accumulation of senescent cells in later life is most likely <a href="https://www.fightaging.org/archives/2019/12/clearance-of-senescent-cells-is-fast-in-youth-slow-in-aging-t…

Source https://www.fightaging.org/archives/2023/05/cellular-senescence-in-skin-as-an-early-sign-of-aging/

While no-one likes to be reminded of it, there are clear, albeit minor signs of aging that arise in as young a stage of life as the late 20s and early 30s. These early manifestations of aging are very poorly understood; perhaps understandably, near all research into mechanisms of aging is focused on late life pathology and its causes. Thus we are left with a very unsatisfactory understanding of what exactly is going in early adult life that makes a mid-30s adult physiologically different from an immediately post-development teenager.

In today’s open access commentary, researchers report on evidence implicating senescent cells in these differences, at least in skin, and this is quite interesting. Present understanding holds that the accumulation of senescent cells in later life is most likely <a href="https://www.fightaging.org/archives/2019/12/clearance-of-senescent-cells-is-fast-in-youth-slow-in-aging-t…

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