Evidence for Head Injuries to Accelerate Cognitive Decline in Following Decades

Source https://www.fightaging.org/archives/2021/03/evidence-for-head-injuries-to-accelerate-cognitive-decline-in-following-decades/

Researchers here present epidemiological evidence for head injuries to leave permanent consequences that accelerate later cognitive decline. Speculatively, the mechanisms by which this might happen could include a increased lasting presence of senescent cells in injured tissue, raising local levels of inflammation. Certainly there is suggestive evidence for some forms of injury, including injuries to the brain, to leave a lasting mark in the form of raised inflammation in tissues. Senescent cells are frequently involved in inflammation-related mechanisms and conditions.

Head injuries did not appear to contribute to brain damage characteristic of Alzheimer’s disease, but might make people more vulnerable to dementia…

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