Mendelian Randomization Supports a Causal Role for the Gut Microbiome in Longevity

Source https://www.fightaging.org/archives/2024/11/mendelian-randomization-supports-a-causal-role-for-the-gut-microbiome-in-longevity/

Animal and human data make a compelling case for differences in the gut microbiome between individuals to contribute to variations in the pace of aging. There is an even better case for age-related changes in the relative proportions of microbial species making up the gut microbiome to accelerate degenerative aging, via loss of beneficial metabolite production and increased chronic inflammation, among other mechanisms. Most directly, fecal microbiota transplantation from young donors to old individuals <a href="https://www.fighta…

Source https://www.fightaging.org/archives/2024/11/mendelian-randomization-supports-a-causal-role-for-the-gut-microbiome-in-longevity/

Animal and human data make a compelling case for differences in the gut microbiome between individuals to contribute to variations in the pace of aging. There is an even better case for age-related changes in the relative proportions of microbial species making up the gut microbiome to accelerate degenerative aging, via loss of beneficial metabolite production and increased chronic inflammation, among other mechanisms. Most directly, fecal microbiota transplantation from young donors to old individuals <a href="https://www.fighta…

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