Source https://www.fightaging.org/archives/2022/01/nanowarming-of-vitrified-kidneys-and-hearts/
Long term low temperature storage of living tissue is an active area of research. Cryoprotectant perfusion allows tissues to vitrify on cooling, minimizing ice crystal formation and thus preserving the small scale structure that is vital to tissue function. The challenge of cooling to vitrification is largely the challenge of obtaining good perfusion of cryoprotectant throughout the tissue, something that is much less of an issue for an isolated organ or tissue sample than it is for an entire animal or human. The more significant challenges are those related to the goal of warming vitrified tissue while retaining full function.
The near term goal for reversible vitrification is to enable more cost-effective organ donation and transplantation. That organ transplantation is a very expensive, uncertain…
Source https://www.fightaging.org/archives/2022/01/nanowarming-of-vitrified-kidneys-and-hearts/
Long term low temperature storage of living tissue is an active area of research. Cryoprotectant perfusion allows tissues to vitrify on cooling, minimizing ice crystal formation and thus preserving the small scale structure that is vital to tissue function. The challenge of cooling to vitrification is largely the challenge of obtaining good perfusion of cryoprotectant throughout the tissue, something that is much less of an issue for an isolated organ or tissue sample than it is for an entire animal or human. The more significant challenges are those related to the goal of warming vitrified tissue while retaining full function.
The near term goal for reversible vitrification is to enable more cost-effective organ donation and transplantation. That organ transplantation is a very expensive, uncertain…
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