Body Mass, Inflammation, and Cognition – What is the Strongest Link?

Source: http://brainblogger.com/2016/11/27/body-mass-inflammation-and-cognition-what-is-the-strongest-link/

Body mass index (BMI) has been linked to inflammation, and systemic inflammation has been linked to decreased cognition. Now, a new study directly links a high BMI to lower cognitive functioning. The current study, published in the journal Brain, Behavior, and Immunity, is the first step in identifying a biologically plausible mechanism for the connection between BMI and cognition.

The authors evaluated 2 cohorts of people aged 50 years and older from the English Longitudinal Study of Aging. One group contained 9000 people and the other contained approximately 12,500.

When the authors correlated BMI, inflammatory markers, and cognition over a 6-year period, the results in both groups were the same: higher BMI was associated with greater cognitive decline.

Specifically, the higher the BMI at the beginning of the study, the greater increase in levels of inflammatory markers (specifically, C-reactive protein [CRP]) over the next 4 years. The change in…

Source: http://brainblogger.com/2016/11/27/body-mass-inflammation-and-cognition-what-is-the-strongest-link/

Body mass index (BMI) has been linked to inflammation, and systemic inflammation has been linked to decreased cognition. Now, a new study directly links a high BMI to lower cognitive functioning. The current study, published in the journal Brain, Behavior, and Immunity, is the first step in identifying a biologically plausible mechanism for the connection between BMI and cognition.

The authors evaluated 2 cohorts of people aged 50 years and older from the English Longitudinal Study of Aging. One group contained 9000 people and the other contained approximately 12,500.

When the authors correlated BMI, inflammatory markers, and cognition over a 6-year period, the results in both groups were the same: higher BMI was associated with greater cognitive decline.

Specifically, the higher the BMI at the beginning of the study, the greater increase in levels of inflammatory markers (specifically, C-reactive protein [CRP]) over the next 4 years. The change in…

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