Source: http://brainblogger.com/2017/05/08/hiv-medications-linked-to-increase-in-alzheimers-disease-protein/
A class of drugs called protease inhibitors have been lifesaving for people with the human immunodeficiency virus (HIV). However, these medications come with a long list of side effects that may include impairments in cognitive function. How protease inhibitors might cause cognitive side effects has remained a mystery for some time. New research from the University of Pennsylvania is beginning to shed light on the answer, and it lies in a protein that is one of the main components of Alzheimer’s disease.
Protease inhibitors work to treat HIV by preventing replication of the HIV virus. The drugs block an enzyme called HIV protease, which cleaves the protein precursors required to produce new viral particles. Inhibiting HIV protease thus prevents the spread of the virus throughout the body. Since the approval of these drugs for clinical use in 1995, the rate of deaths from HIV has declined drastically. A typical HIV patient takes a combination of protease inhibitors and other…
Source: http://brainblogger.com/2017/05/08/hiv-medications-linked-to-increase-in-alzheimers-disease-protein/
A class of drugs called protease inhibitors have been lifesaving for people with the human immunodeficiency virus (HIV). However, these medications come with a long list of side effects that may include impairments in cognitive function. How protease inhibitors might cause cognitive side effects has remained a mystery for some time. New research from the University of Pennsylvania is beginning to shed light on the answer, and it lies in a protein that is one of the main components of Alzheimer’s disease.
Protease inhibitors work to treat HIV by preventing replication of the HIV virus. The drugs block an enzyme called HIV protease, which cleaves the protein precursors required to produce new viral particles. Inhibiting HIV protease thus prevents the spread of the virus throughout the body. Since the approval of these drugs for clinical use in 1995, the rate of deaths from HIV has declined drastically. A typical HIV patient takes a combination of protease inhibitors and other…
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