Source https://www.fightaging.org/archives/2020/04/inhibition-of-atm-kinase-reduces-cellular-senescence-and-sasp-in-progeroid-mice/
Progeroid mice with DNA repair deficiencies exhibit an accelerated formation of senescent cells and manifestation of age-related conditions. This class of animal model has been used in research relating to cellular senescence in order to cost-effectively demonstrate that targeted removal of senescent cells is beneficial. However, one still needs to be careful when drawing conclusions based on their peculiar biochemistry. Progeria of this nature is quite unlike normal aging at the detail level.
Cells become senescent in response to reaching the Hayflick limi…
Source https://www.fightaging.org/archives/2020/04/inhibition-of-atm-kinase-reduces-cellular-senescence-and-sasp-in-progeroid-mice/
Progeroid mice with DNA repair deficiencies exhibit an accelerated formation of senescent cells and manifestation of age-related conditions. This class of animal model has been used in research relating to cellular senescence in order to cost-effectively demonstrate that targeted removal of senescent cells is beneficial. However, one still needs to be careful when drawing conclusions based on their peculiar biochemistry. Progeria of this nature is quite unlike normal aging at the detail level.
Cells become senescent in response to reaching the Hayflick limi…
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