To Treat Alzheimer's Disease, Target the Treatment of Aging

Source https://www.fightaging.org/archives/2024/05/to-treat-alzheimers-disease-target-the-treatment-of-aging/

One of the important points made by advocates for the treatment of aging is that one cannot distinguish between aging and age-related disease. They are one and the same. There is no magical state of “healthy aging” in which one doesn’t suffer eventual disease. A decline of function in aging that does not rise to the level required to call it a disease is the subclinical stage of that disease; all the same damage has taken place under the hood, just less of it. Conversely, an age-related disease is just another facet of aging, a collection of damage and consequences of damage that becomes sizable enough to reach the definition of disease. Whether or not any specific age-related dysfunction is called a disease is just a matter of whether the degree of dysfunction is on one side or another of an arbitrary line drawn in the sand.

The authors o…

Source https://www.fightaging.org/archives/2024/05/to-treat-alzheimers-disease-target-the-treatment-of-aging/

One of the important points made by advocates for the treatment of aging is that one cannot distinguish between aging and age-related disease. They are one and the same. There is no magical state of “healthy aging” in which one doesn’t suffer eventual disease. A decline of function in aging that does not rise to the level required to call it a disease is the subclinical stage of that disease; all the same damage has taken place under the hood, just less of it. Conversely, an age-related disease is just another facet of aging, a collection of damage and consequences of damage that becomes sizable enough to reach the definition of disease. Whether or not any specific age-related dysfunction is called a disease is just a matter of whether the degree of dysfunction is on one side or another of an arbitrary line drawn in the sand.

The authors o…

Skinny Fat: When You Look Thin But Aren't Fit

Source https://greatist.com/health/skinny-fat

“Skinny fat” is a non-medical term for a body that looks slim but lacks muscle tone or strength.

If anyone’s ever called you “skinny fat,” you know it’s not exactly a compliment. Describing your body type this way is confusing or even insulting. Yet, despite its not-so-nice ring, there’s an actual physical phenomenon behind this concept.

Here’s what it looks like to be “skinny fat,” plus what it means for your health.

What does skinny fat mean?

Skinny fat isn’t a clinical term. Instead, it’s a general description of having a “normal” or even low weight while having metabolic health problems and lower-than-optimal muscle mass.

Researchers have identified this occurrence when studying populations in Asia, where many people have metabolic disorders like type 2 diabete…

Source https://greatist.com/health/skinny-fat

“Skinny fat” is a non-medical term for a body that looks slim but lacks muscle tone or strength.

If anyone’s ever called you “skinny fat,” you know it’s not exactly a compliment. Describing your body type this way is confusing or even insulting. Yet, despite its not-so-nice ring, there’s an actual physical phenomenon behind this concept.

Here’s what it looks like to be “skinny fat,” plus what it means for your health.

What does skinny fat mean?

Skinny fat isn’t a clinical term. Instead, it’s a general description of having a “normal” or even low weight while having metabolic health problems and lower-than-optimal muscle mass.

Researchers have identified this occurrence when studying populations in Asia, where many people have metabolic disorders like type 2 diabete…

Kettlebell Snatch: Get Into the Swing of Things

Source https://greatist.com/fitness/kettlebell-snatch

A kettlebell snatch is a full-body exercise you can perform just about anywhere. Learn how to perform this simple but effective move.  

Compact and convenient, a kettlebell is a great addition to your at-home or gym-based workouts. This little weight shaped like an old-timey alarm clock (or slightly wonky Mickey Mouse head) offers benefits for strength while being easy to grip and maneuver. One popular exercise to do with it is the so-called “snatch.”

Read on to learn how to master the kettlebell snatch, plus its potential benefits for your bod.

kettlebell snatch
FreshSplash/Getty Images

How to do a ket…

Source https://greatist.com/fitness/kettlebell-snatch

A kettlebell snatch is a full-body exercise you can perform just about anywhere. Learn how to perform this simple but effective move.  

Compact and convenient, a kettlebell is a great addition to your at-home or gym-based workouts. This little weight shaped like an old-timey alarm clock (or slightly wonky Mickey Mouse head) offers benefits for strength while being easy to grip and maneuver. One popular exercise to do with it is the so-called “snatch.”

Read on to learn how to master the kettlebell snatch, plus its potential benefits for your bod.

kettlebell snatch
FreshSplash/Getty Images

How to do a ket…

Cankles: Causes, Treatments, and When to See a Doctor

Source https://greatist.com/health/cankles

Thicker ankles are usually harmless. However, swollen ankles could potentially signal a deeper medical issue.

From hip dips to cankles, it seems like society can turn perfectly normal body parts into a prob. Cankles is a not-so-nice slang term for ankles that blend into the feet. Aesthetically speaking, there’s absolutely nothing wrong with them.

Thicker bones and more fat in the ankles may simply be due to genes and lifestyle factors. But sometimes, the ankles may swell and retain fluid due to an underlying medical prob like diabetes or hypothyroidism.

Here’s what to know!

cankles
Wang Yukun/Getty Images

<h2 id="causes" data-toc-label="Causes…

Source https://greatist.com/health/cankles

Thicker ankles are usually harmless. However, swollen ankles could potentially signal a deeper medical issue.

From hip dips to cankles, it seems like society can turn perfectly normal body parts into a prob. Cankles is a not-so-nice slang term for ankles that blend into the feet. Aesthetically speaking, there’s absolutely nothing wrong with them.

Thicker bones and more fat in the ankles may simply be due to genes and lifestyle factors. But sometimes, the ankles may swell and retain fluid due to an underlying medical prob like diabetes or hypothyroidism.

Here’s what to know!

cankles
Wang Yukun/Getty Images

<h2 id="causes" data-toc-label="Causes…

Create with Us!

Source https://seniorplanet.org/articles-come-create/

Creating something by hand can be a rewarding and stress-relieving activity, but if you can’t find the time – Senior Planet has an answer.  

The post Create with Us! appeared first on Senior Planet from AARP.

Source https://seniorplanet.org/articles-come-create/

Creating something by hand can be a rewarding and stress-relieving activity, but if you can’t find the time – Senior Planet has an answer.  

The post Create with Us! appeared first on Senior Planet from AARP.

In Search of Natural Senolytics to Substitute for Dasatinib

Source https://www.fightaging.org/archives/2024/05/in-search-of-natural-senolytics-to-substitute-for-dasatinib/

Dasatinib and quercetin used in combination clears a fraction of lingering senescent cells in aging mice, producing a sizable degree of rejuvenation, and reversal of aspects of many different age-related conditions. In humans, clinical trials are underway at a sedate pace. Dasatinib is a chemotherapeutic small molecule, while quercetin is a plant extract flavonol. Here, researchers discuss their search for plant extract alternatives that mimic the effects of dasatinib, in the hopes of produ…

Source https://www.fightaging.org/archives/2024/05/in-search-of-natural-senolytics-to-substitute-for-dasatinib/

Dasatinib and quercetin used in combination clears a fraction of lingering senescent cells in aging mice, producing a sizable degree of rejuvenation, and reversal of aspects of many different age-related conditions. In humans, clinical trials are underway at a sedate pace. Dasatinib is a chemotherapeutic small molecule, while quercetin is a plant extract flavonol. Here, researchers discuss their search for plant extract alternatives that mimic the effects of dasatinib, in the hopes of produ…

Senior Planet Book Club: Joan Is Okay by Weike Wang

Source https://seniorplanet.org/articles-senior-planet-book-club-joan-is-okay-by-weike-wang/

The votes are in! Join our book club and enjoy the discussion about Joan Is Okay!

The post Senior Planet Book Club: <em>Joan Is Okay</em> by Weike Wang appeared first on Senior Planet from AARP.

Source https://seniorplanet.org/articles-senior-planet-book-club-joan-is-okay-by-weike-wang/

The votes are in! Join our book club and enjoy the discussion about Joan Is Okay!

The post Senior Planet Book Club: <em>Joan Is Okay</em> by Weike Wang appeared first on Senior Planet from AARP.

Innate Immune cGAS/STING Signaling is Both Necessary and Pathological

Source https://www.fightaging.org/archives/2024/05/innate-immune-cgas-sting-signaling-is-both-necessary-and-pathological/

Chronic, unresolved inflammation is a feature of aging. When the immune system is constantly active in this way, the consequent altered cell behavior throughout the body becomes disruptive to tissue and organ function, harmful to the individual. Chronic inflammation accelerates the onset and progression of all of the common fatal age-related conditions. This unwanted inflammatory signaling arises from many different roots, including the growing presence of senescent cells, but also the interaction of innate immune sensors with other forms of age-related dysfunction. For example, damage-associated molecular pa…

Source https://www.fightaging.org/archives/2024/05/innate-immune-cgas-sting-signaling-is-both-necessary-and-pathological/

Chronic, unresolved inflammation is a feature of aging. When the immune system is constantly active in this way, the consequent altered cell behavior throughout the body becomes disruptive to tissue and organ function, harmful to the individual. Chronic inflammation accelerates the onset and progression of all of the common fatal age-related conditions. This unwanted inflammatory signaling arises from many different roots, including the growing presence of senescent cells, but also the interaction of innate immune sensors with other forms of age-related dysfunction. For example, damage-associated molecular pa…

How I Found Purpose When I Lost It at Work

Source https://tinybuddha.com/blog/how-i-found-purpose-when-i-lost-it-at-work/

“The mystery of human existence lies not in just staying alive, but in finding something to live for.” ~Fyodor Dostoyevsky

When I was in my last semester of college in 2016, I got my first paid job working in libraries as a childrens library assistant. I can remember the passion and sense of purpose I initially felt when taking this job. The idea that, every day, Id be helping foster a love of reading in kids felt like a worthwhile career.

Reading supports cognitive development in children. It enhances language skills and improves concentration. It encourages creativity and even fosters empathy, as it in…

Source https://tinybuddha.com/blog/how-i-found-purpose-when-i-lost-it-at-work/

“The mystery of human existence lies not in just staying alive, but in finding something to live for.” ~Fyodor Dostoyevsky

When I was in my last semester of college in 2016, I got my first paid job working in libraries as a childrens library assistant. I can remember the passion and sense of purpose I initially felt when taking this job. The idea that, every day, Id be helping foster a love of reading in kids felt like a worthwhile career.

Reading supports cognitive development in children. It enhances language skills and improves concentration. It encourages creativity and even fosters empathy, as it in…

The BEST Gluten-Free Vanilla Cake (1 Bowl!)

Source https://minimalistbaker.com/the-best-gluten-free-vanilla-cake/

The BEST Gluten-Free Vanilla Cake (1 Bowl!)

Friends, meet the vanilla cake of your DREAMS! It’s super fluffy, perfectly moist, undetectably gluten-free (& dairy-free), and seriously…the BEST. It’s impressive enough for a birthday or even a wedding!

Bonus? It’s also SO easy to make, with simple methods, 1 bowl, and 9 ingredients. Preheat your oven. Let them eat cake!

This cake could not be easier to make! Simply whisk, pour, bake, and enjoy your cake, for goodness sake!

The BEST Gluten-Free Vanilla Cake (1 Bowl!) from Minimalist …

Source https://minimalistbaker.com/the-best-gluten-free-vanilla-cake/

The BEST Gluten-Free Vanilla Cake (1 Bowl!)

Friends, meet the vanilla cake of your DREAMS! It’s super fluffy, perfectly moist, undetectably gluten-free (& dairy-free), and seriously…the BEST. It’s impressive enough for a birthday or even a wedding!

Bonus? It’s also SO easy to make, with simple methods, 1 bowl, and 9 ingredients. Preheat your oven. Let them eat cake!

This cake could not be easier to make! Simply whisk, pour, bake, and enjoy your cake, for goodness sake!

The BEST Gluten-Free Vanilla Cake (1 Bowl!) from Minimalist …

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