Source https://www.fightaging.org/archives/2021/02/correlating-cancer-risk-with-epigenetic-age/
Epigenetic clocks measure changes in epigenetic marks on the genome that correlate with age. Greater epigenetic change at a given chronological age indicates a greater burden of biological aging, more damage and dysfunction. It remains to be determined with any great rigor as to exactly which damage and dysfunction causes any given set of epigenetic changes, which makes it challenging to use epigenetic age as a measure of success in the development of rejuvenation therapies. Development continues apace, however. For example, researchers here show that second generation epigenetic clocks show a greater correlation with risk of cancer than is the case for first generation clocks.
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Source https://www.fightaging.org/archives/2021/02/correlating-cancer-risk-with-epigenetic-age/
Epigenetic clocks measure changes in epigenetic marks on the genome that correlate with age. Greater epigenetic change at a given chronological age indicates a greater burden of biological aging, more damage and dysfunction. It remains to be determined with any great rigor as to exactly which damage and dysfunction causes any given set of epigenetic changes, which makes it challenging to use epigenetic age as a measure of success in the development of rejuvenation therapies. Development continues apace, however. For example, researchers here show that second generation epigenetic clocks show a greater correlation with risk of cancer than is the case for first generation clocks.
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