Source https://www.fightaging.org/archives/2023/02/reviewing-cellular-senescence-in-idiopathic-pulmonary-fibrosis/
Fibrosis is the excessive deposition of extracellular matrix, forming scar-like structures that are disruptive to tissue function. It is a feature of aging in many organs, such as heart, liver, kidney, and lungs, and when particularly pronounced it is declared to be fibrotic disease. So far medical science has struggled to make much headway in the reversal of fibrosis once it is established, which makes these conditions particularly threatening.
Fibrosis is connected to the chronic inflammation characteristic of old age, and in recent years evidence has amassed for senescent cells to drive fibrosis. Senescent cell…
Source https://www.fightaging.org/archives/2023/02/reviewing-cellular-senescence-in-idiopathic-pulmonary-fibrosis/
Fibrosis is the excessive deposition of extracellular matrix, forming scar-like structures that are disruptive to tissue function. It is a feature of aging in many organs, such as heart, liver, kidney, and lungs, and when particularly pronounced it is declared to be fibrotic disease. So far medical science has struggled to make much headway in the reversal of fibrosis once it is established, which makes these conditions particularly threatening.
Fibrosis is connected to the chronic inflammation characteristic of old age, and in recent years evidence has amassed for senescent cells to drive fibrosis. Senescent cell…
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