Source https://www.fightaging.org/archives/2023/04/modeling-the-contribution-of-cellular-senescence-to-the-tradeoff-between-cancer-risk-and-aging/
Researchers consider that the state of late life health in humans, and the mechanisms involved, are a balance between risk of death by cancer and risk of death by loss of tissue function. Cancer risk is increased by the activity of damaged cells, particularly stem cells, in a dysfunctional tissue environment, while loss of tissue function is accelerated by suppressing that activity. Tissue must be maintained, such as via a supply of new cells to replace losses, and cells must be active in order for that maintenance to occur.
Cellular senescence is a part of this balance of benefit and harm. Cellular senescence is a cancer suppression mechanism, h…
Source https://www.fightaging.org/archives/2023/04/modeling-the-contribution-of-cellular-senescence-to-the-tradeoff-between-cancer-risk-and-aging/
Researchers consider that the state of late life health in humans, and the mechanisms involved, are a balance between risk of death by cancer and risk of death by loss of tissue function. Cancer risk is increased by the activity of damaged cells, particularly stem cells, in a dysfunctional tissue environment, while loss of tissue function is accelerated by suppressing that activity. Tissue must be maintained, such as via a supply of new cells to replace losses, and cells must be active in order for that maintenance to occur.
Cellular senescence is a part of this balance of benefit and harm. Cellular senescence is a cancer suppression mechanism, h…
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