Regeneration from injury is an intricate dance of many different cell types: stem cells, somatic cells, cells that become senescent, and innate immune cells such as macrophages. This is true of every higher species, but what is the meaningful difference between species capable of regenerating entire limbs and internal organs, such as salamanders, and species that scar and exhibit only partial regeneration of lost tissue, such as near all mammals? In recent years, researchers have discovered that <a href="https://www.fightaging.org/archives/2017/05/macrophages-and-possibly-senescent-cells-are-the-keys-to-the-exceptional-regeneration-of-af…
Senescent Cells Induce Dedifferentiation in Salamander Regeneration
Regeneration from injury is an intricate dance of many different cell types: stem cells, somatic cells, cells that become senescent, and innate immune cells such as macrophages. This is true of every higher species, but what is the meaningful difference between species capable of regenerating entire limbs and internal organs, such as salamanders, and species that scar and exhibit only partial regeneration of lost tissue, such as near all mammals? In recent years, researchers have discovered that <a href="https://www.fightaging.org/archives/2017/05/macrophages-and-possibly-senescent-cells-are-the-keys-to-the-exceptional-regeneration-of-af…