Cellular Senescence in the Aging of Bone Tissue

Source https://www.fightaging.org/archives/2023/07/cellular-senescence-in-the-aging-of-bone-tissue/

Cells become senescent constantly, throughout life and throughout the body. Most such cells have reached the Hayflick limit on replication, but cells can also become senescent in response to damage, stress, or the signaling of other senescent cells. In youth, senescent cells are efficiently cleared by the immune system, but this clearance falters with age for reasons that are incompletely understood at the present time. The consequence of a mismatch between pace of creation and pace of clearance is a growing <a href="https://www.fightaging.org/archives/2014/07/aiming-to-remove-t…

Source https://www.fightaging.org/archives/2023/07/cellular-senescence-in-the-aging-of-bone-tissue/

Cells become senescent constantly, throughout life and throughout the body. Most such cells have reached the Hayflick limit on replication, but cells can also become senescent in response to damage, stress, or the signaling of other senescent cells. In youth, senescent cells are efficiently cleared by the immune system, but this clearance falters with age for reasons that are incompletely understood at the present time. The consequence of a mismatch between pace of creation and pace of clearance is a growing <a href="https://www.fightaging.org/archives/2014/07/aiming-to-remove-t…

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