Transferring the Naked Mole Rat Hyaluronan Synthase 2 Gene Into Mice Reduces Cancer Incidence, Extends Life

Source https://www.fightaging.org/archives/2023/08/transferring-the-naked-mole-rat-hyaluronan-synthase-2-gene-into-mice-reduces-cancer-incidence-extends-life/

Naked mole rats live far longer than similarly sized mammals, and are near immune to cancer. One of the mechanisms of cancer resistance involves the production of a different form of high molecular weight hyaluronan, and much more of it, improving the anti-cancer mechanism of contact inhibition. In addition, other mechanisms derived from changes in hyaluronan may affect life span through improved cellular function, but this is less well explored. Researchers here take the naked mole-rat version of the gene for high molecular weight hyoluronan, <a href="https://en.wikipedia.org/wiki/HAS…

Source https://www.fightaging.org/archives/2023/08/transferring-the-naked-mole-rat-hyaluronan-synthase-2-gene-into-mice-reduces-cancer-incidence-extends-life/

Naked mole rats live far longer than similarly sized mammals, and are near immune to cancer. One of the mechanisms of cancer resistance involves the production of a different form of high molecular weight hyaluronan, and much more of it, improving the anti-cancer mechanism of contact inhibition. In addition, other mechanisms derived from changes in hyaluronan may affect life span through improved cellular function, but this is less well explored. Researchers here take the naked mole-rat version of the gene for high molecular weight hyoluronan, <a href="https://en.wikipedia.org/wiki/HAS…

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