Chronic inflammation remains an important contributing process in the development of age-related dysfunction and disease, one that is presently difficult to address. This unresolved inflammation is a direct consequence of a number of different causes of aging. They include mitochondrial dysfunction leading to mislocalization of mitochondrial DNA into the cytoplasm, where it triggers responses evolved to detect bacterial infection, as well as the now well-studied burden of <a href="https:/…
Towards an Improved Suppression of Maladaptive Inflammation
Chronic inflammation remains an important contributing process in the development of age-related dysfunction and disease, one that is presently difficult to address. This unresolved inflammation is a direct consequence of a number of different causes of aging. They include mitochondrial dysfunction leading to mislocalization of mitochondrial DNA into the cytoplasm, where it triggers responses evolved to detect bacterial infection, as well as the now well-studied burden of <a href="https:/…