Source https://www.fightaging.org/archives/2023/10/senescent-cells-contribute-to-the-degeneration-of-the-retinal-vasculature/
Senescent cells accumulate with age throughout the body. While their numbers remain a small fraction of all cells in a tissue, even in late life, senescent cells produce an outsized harm to tissue structure and function via a continual, disruptive, pro-growth, pro-inflammatory signaling, the senescence-associated secretory phenotype (SASP). Researchers have demonstrated, in animal models, that senescent cells directly contribute to the onset and progression of many distinct age-related conditions. Further, it has been shown in animal models that clearing senescent cells throughout the body can rapidly reverse pathology in these conditions.
Degeneration of the vasculature is involved in <a href="http…
Source https://www.fightaging.org/archives/2023/10/senescent-cells-contribute-to-the-degeneration-of-the-retinal-vasculature/
Senescent cells accumulate with age throughout the body. While their numbers remain a small fraction of all cells in a tissue, even in late life, senescent cells produce an outsized harm to tissue structure and function via a continual, disruptive, pro-growth, pro-inflammatory signaling, the senescence-associated secretory phenotype (SASP). Researchers have demonstrated, in animal models, that senescent cells directly contribute to the onset and progression of many distinct age-related conditions. Further, it has been shown in animal models that clearing senescent cells throughout the body can rapidly reverse pathology in these conditions.
Degeneration of the vasculature is involved in <a href="http…
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