The Aging of the Gut Microbiome is Different by Sex and Mitochondrial Haplotype

Source https://www.fightaging.org/archives/2025/03/the-aging-of-the-gut-microbiome-is-different-by-sex-and-mitochondrial-haplotype/

Researchers here find that age-related changes in the gut microbiome are quite different by sex, and are influenced by the host’s mitochondrial haplotype as well. It is now well known that changes occur in the gut microbiome with age, and these changes contribute to age-related degeneration via reduced production of beneficial metabolites and increased inflammation – but there may well be a great deal of variation from individual to individual. The work noted here was conducted in rats, so it remains to be seen as to whether matters are much the same in humans.

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