Elastin is an important component of the extracellular matrix in flexible tissues. It is, as the name might suggest, necessary for tissue elasticity. Elastin fibers in the extracellular matrix become damaged with age, and this process is thought to be important in a number of ways, not just because it alters the structural properties of the tissue, but also because it changes cell behavior for the worse. The presence of elastin fragments can provoke inflammation or other maladaptive responses, for example. It isn’t entirely clear how best to tackle this aspect of aging, as elastin fib…
Elastin Expression May Reduce Cellular Senescence via Interactions with Mitochondria
Elastin is an important component of the extracellular matrix in flexible tissues. It is, as the name might suggest, necessary for tissue elasticity. Elastin fibers in the extracellular matrix become damaged with age, and this process is thought to be important in a number of ways, not just because it alters the structural properties of the tissue, but also because it changes cell behavior for the worse. The presence of elastin fragments can provoke inflammation or other maladaptive responses, for example. It isn’t entirely clear how best to tackle this aspect of aging, as elastin fib…