Source https://www.fightaging.org/archives/2025/04/a-study-of-oneskins-topical-senotherapeutic-os-1-on-skin-function/
Senescent cells accumulate with age in all tissues, including skin. These errant cells secrete inflammatory signals that degrade tissue structure and function when sustained for the long term. OneSkin is one of the earlier longevity industry companies, built on the development of a senotherapeutic compound called OS-01. The founders chose to take the topical, cosmetics regulatory pathway to market. It is a lot faster than drug development, but has drawbacks, such as being taken less seriously by the scientific community.
OS-01 reduces the burden of senescence in tissue models of skin, suggesting that it encourages senescent cells to undergo <…
Source https://www.fightaging.org/archives/2025/04/a-study-of-oneskins-topical-senotherapeutic-os-1-on-skin-function/
Senescent cells accumulate with age in all tissues, including skin. These errant cells secrete inflammatory signals that degrade tissue structure and function when sustained for the long term. OneSkin is one of the earlier longevity industry companies, built on the development of a senotherapeutic compound called OS-01. The founders chose to take the topical, cosmetics regulatory pathway to market. It is a lot faster than drug development, but has drawbacks, such as being taken less seriously by the scientific community.
OS-01 reduces the burden of senescence in tissue models of skin, suggesting that it encourages senescent cells to undergo <…
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