A Physical Activity Study in Obese Individuals Suggests the Burden of Senescent Cells is to Some Degree Dynamic

Source https://www.fightaging.org/archives/2025/04/a-physical-activity-study-in-obese-individuals-suggests-the-burden-of-senescent-cells-is-to-some-degree-dynamic/

To what degree is the burden of senescent cells in the tissues of old or obese people dynamic, capable of being reduced by circumstances? Cells become senescent constantly throughout life, and are then cleared by the immune system or destroy themselves via programmed cell death mechanisms. That clearance falters with advancing age, however. We might also think that the pace at which cells become senescent is likely higher in tissues stressed by the molecular damage of aging or by the aberrant <a href="https…

Source https://www.fightaging.org/archives/2025/04/a-physical-activity-study-in-obese-individuals-suggests-the-burden-of-senescent-cells-is-to-some-degree-dynamic/

To what degree is the burden of senescent cells in the tissues of old or obese people dynamic, capable of being reduced by circumstances? Cells become senescent constantly throughout life, and are then cleared by the immune system or destroy themselves via programmed cell death mechanisms. That clearance falters with advancing age, however. We might also think that the pace at which cells become senescent is likely higher in tissues stressed by the molecular damage of aging or by the aberrant <a href="https…

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