Source https://www.fightaging.org/archives/2025/04/senescent-endothelial-cells-contribute-to-atherosclerosis-via-cap1-signaling/
The inflammatory signaling produced by senescent cells is harmful when sustained over the long term, and the number of these cells grows with age. Much of the signaling produced by cells is carried in extracellular vesicles, and here researches identify CAP1 as a important cargo in senescent cell extracellular vesicles that accelerates dysfunction and increases the burden of cellular senescence in the endothelium that lines blood vessels. Senescence of endothelial cells is a significant contributing factor in the formation and growth of atherosclerotic plaques.
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Source https://www.fightaging.org/archives/2025/04/senescent-endothelial-cells-contribute-to-atherosclerosis-via-cap1-signaling/
The inflammatory signaling produced by senescent cells is harmful when sustained over the long term, and the number of these cells grows with age. Much of the signaling produced by cells is carried in extracellular vesicles, and here researches identify CAP1 as a important cargo in senescent cell extracellular vesicles that accelerates dysfunction and increases the burden of cellular senescence in the endothelium that lines blood vessels. Senescence of endothelial cells is a significant contributing factor in the formation and growth of atherosclerotic plaques.
<bloc…
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