Source https://www.fightaging.org/archives/2025/04/reviewing-the-present-state-of-aging-clocks/
This open access paper could serve as an introduction to aging clocks for someone who has previously given little attention to the ongoing attempts to build ways to quickly and cost-effectively measure biological age. Near every complex set of biological data obtained from an individual can be used to build clocks that estimate age. The present major challenge is the inability to trust the results of any specific clock for any specific scenario involving the use of therapies to treat aging. There is next to no understanding of how in detail the clock data is driven by mechanisms and dysfunctions of aging, and thus no ability to predict ahead of time whether a clock will give useful answers for any given therapy targeting a mechanism of aging. Clocks must be calibrated to their uses, and this is a slow and expensiv…
Source https://www.fightaging.org/archives/2025/04/reviewing-the-present-state-of-aging-clocks/
This open access paper could serve as an introduction to aging clocks for someone who has previously given little attention to the ongoing attempts to build ways to quickly and cost-effectively measure biological age. Near every complex set of biological data obtained from an individual can be used to build clocks that estimate age. The present major challenge is the inability to trust the results of any specific clock for any specific scenario involving the use of therapies to treat aging. There is next to no understanding of how in detail the clock data is driven by mechanisms and dysfunctions of aging, and thus no ability to predict ahead of time whether a clock will give useful answers for any given therapy targeting a mechanism of aging. Clocks must be calibrated to their uses, and this is a slow and expensiv…
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