Joint Aging Starts Early, Particularly in Overweight Individuals

Source https://www.fightaging.org/archives/2025/05/joint-aging-starts-early-particularly-in-overweight-individuals/

Measurable early signs of aging are interesting because they can serve as an easier platform for the development of therapies: there are more patients, and the patients are more physically robust. Here, researchers show that wear and tear damage to cartilage can be seen as early as the 30s, particularly in people who are overweight. Cartilage damage remains a challenge for the medical community, though a range of efforts are underway to develop and assess regenerative therapies to address this issue. That younger people might be candidates for those therapies can only increase the incentives for developers.

Mild structural changes visible in knee MRI scans are already common among adults in their thirties – even in those without knee pain or other symptoms. A stu…

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