Immune system function declines with age. Immune cells become more inflammatory, but at the same time less capable. Further, populations of malfunctioning and harmful immune cells grow in number. The immune system is enormously complex, and one might argue that this is the primary reason why researchers have yet to produce a full accounting of the details of immune aging. Producing data is straightforward, but connecting the many different views of cell state that can be produced via omics technologies into a coherent whole is very much more challenging. Here, researchers focus on epigenetic…
Reviewing What is Known of Epigenetic Changes in Aged T Cells
Immune system function declines with age. Immune cells become more inflammatory, but at the same time less capable. Further, populations of malfunctioning and harmful immune cells grow in number. The immune system is enormously complex, and one might argue that this is the primary reason why researchers have yet to produce a full accounting of the details of immune aging. Producing data is straightforward, but connecting the many different views of cell state that can be produced via omics technologies into a coherent whole is very much more challenging. Here, researchers focus on epigenetic…