Source https://www.fightaging.org/archives/2025/11/manufacturing-cell-vesicles-for-therapy-via-membrane-extrusion/
Therapeutic use of extracellular vesicles seems likely to replace much of the present use of stem cell therapy, as these first generation stem cell transplantation therapies achieve benefits near entirely via the signaling generated by the transplanted cells in the short period of time in which they survive. Much of that signaling takes the form of extracellular vesicles, membrane-wrapped packages of molecules. Vesicles can be harvested from cell cultures, and are much easier to store and transport than is the case for cells, allowing centralization of the harder part of the manufacturing process that is managing stem cell cultures.
In recent years researchers have moved on from simply harvesting vesicles to finding ways to induce cells to create a lot more vesicles than is …
Source https://www.fightaging.org/archives/2025/11/manufacturing-cell-vesicles-for-therapy-via-membrane-extrusion/
Therapeutic use of extracellular vesicles seems likely to replace much of the present use of stem cell therapy, as these first generation stem cell transplantation therapies achieve benefits near entirely via the signaling generated by the transplanted cells in the short period of time in which they survive. Much of that signaling takes the form of extracellular vesicles, membrane-wrapped packages of molecules. Vesicles can be harvested from cell cultures, and are much easier to store and transport than is the case for cells, allowing centralization of the harder part of the manufacturing process that is managing stem cell cultures.
In recent years researchers have moved on from simply harvesting vesicles to finding ways to induce cells to create a lot more vesicles than is …
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