Shebah, 68 – Five Exercises to Age Well and Enhance Longevity

Source https://seniorplanet.org/articles-sa-shebah-longevity/

Strength, balance, mobility, and more! Sponsored Athlete Shebah, 68, shares five fitness modalities for older adults to focus on – and invites you to train together on Nov. 19.

The post Shebah, 68 – Five Exercises to Age Well and Enhance Longevity appeared first on Senior Planet from AARP.

Source https://seniorplanet.org/articles-sa-shebah-longevity/

Strength, balance, mobility, and more! Sponsored Athlete Shebah, 68, shares five fitness modalities for older adults to focus on – and invites you to train together on Nov. 19.

The post Shebah, 68 – Five Exercises to Age Well and Enhance Longevity appeared first on Senior Planet from AARP.

If you need to hear this…

Source https://www.nerdfitness.com/blog/youre-doing-great/

I’ve gotten several messages from readers lately that have my Spidey-senses tingling.

Here are a few examples:

“I’ve been working out 3x/week for 16-weeks. It’s going well and I’m seeing changes, but I’m not sure if my progress is good enough or what I’m missing.”

“I’m worried my goals aren’t specific enough. I feel a bit lost and there’s so much out there to consider. I’m not sure if I’ve got it all right.”

It echoes a question I’ve talked about before: What does “en…

Source https://www.nerdfitness.com/blog/youre-doing-great/

I’ve gotten several messages from readers lately that have my Spidey-senses tingling.

Here are a few examples:

“I’ve been working out 3x/week for 16-weeks. It’s going well and I’m seeing changes, but I’m not sure if my progress is good enough or what I’m missing.”

“I’m worried my goals aren’t specific enough. I feel a bit lost and there’s so much out there to consider. I’m not sure if I’ve got it all right.”

It echoes a question I’ve talked about before: What does “en…

The AI-enabled future for older adults comes into focus

Source https://www.ageinplacetech.com/blog/ai-enabled-future-older-adults-comes-focus

And just in time — we are on the cusp of the utility of AI agents. Ironically, or maybe not so much, that improvement is inversely proportional to the diminished availability of people to solve our problemsWe see bits and pieces of the decline of people in processes we need.  Whether it is the sign-in kiosk in the healthcare waiting room, the check-in process at the airport, automated creation of pharmacy refill requests, or the customer service ‘interface’ that is now nearly all AI. And screaming ‘agent’ may still not bring the actual person to the phone. What’s positive and likely? [Information is drawn from interviews about “The Future of AI an…

Source https://www.ageinplacetech.com/blog/ai-enabled-future-older-adults-comes-focus

And just in time — we are on the cusp of the utility of AI agents. Ironically, or maybe not so much, that improvement is inversely proportional to the diminished availability of people to solve our problemsWe see bits and pieces of the decline of people in processes we need.  Whether it is the sign-in kiosk in the healthcare waiting room, the check-in process at the airport, automated creation of pharmacy refill requests, or the customer service ‘interface’ that is now nearly all AI. And screaming ‘agent’ may still not bring the actual person to the phone. What’s positive and likely? [Information is drawn from interviews about “The Future of AI an…

Further Investigation of PU.1 and Microglial Inflammation in the Aging Brain

Source https://www.fightaging.org/archives/2025/11/further-investigation-of-pu-1-and-microglial-inflammation-in-the-aging-brain/

Microglia are innate immune cells resident in the brain. They are broadly similar in behavior to the macrophages found elsewhere in the body, with an added portfolio of duties relating to maintenance of the synaptic connections that link neurons to form neural networks. Researchers have provided evidence for microglia to both harm and help the aging brain, with various subpopulations of microglia either acting to cause damage and dysfunction or attempting to resist that damage and dysfunction. On…

Source https://www.fightaging.org/archives/2025/11/further-investigation-of-pu-1-and-microglial-inflammation-in-the-aging-brain/

Microglia are innate immune cells resident in the brain. They are broadly similar in behavior to the macrophages found elsewhere in the body, with an added portfolio of duties relating to maintenance of the synaptic connections that link neurons to form neural networks. Researchers have provided evidence for microglia to both harm and help the aging brain, with various subpopulations of microglia either acting to cause damage and dysfunction or attempting to resist that damage and dysfunction. On…

Chaperone Mediated Autophagy is Necessary for for Brown Adipose Tissue Function

Source https://www.fightaging.org/archives/2025/11/chaperone-mediated-autophagy-is-necessary-for-for-brown-adipose-tissue-function/

Brown adipose tissue conducts thermogenesis and its activities have been found to be beneficial to the operation of metabolism. Thus a greater proportion of brown adipose tissue versus other types of fat tissue is protective in the context of aging. Unfortunately brown adipose tissue function declines with age, and here researchers provide evidence for this form of fat tissue aging to be caused by a decline in the efficacy of chaperone mediated autophagy, also a feature of aging…

Source https://www.fightaging.org/archives/2025/11/chaperone-mediated-autophagy-is-necessary-for-for-brown-adipose-tissue-function/

Brown adipose tissue conducts thermogenesis and its activities have been found to be beneficial to the operation of metabolism. Thus a greater proportion of brown adipose tissue versus other types of fat tissue is protective in the context of aging. Unfortunately brown adipose tissue function declines with age, and here researchers provide evidence for this form of fat tissue aging to be caused by a decline in the efficacy of chaperone mediated autophagy, also a feature of aging…

Podcast Ep. 513 | The Sound of Life

Source https://www.theminimalists.com/p513/

The Minimalists talk about making time for frivolous pursuits, what we’re willing to sacrifice for the important things, clutter that shows up unexpectedly, five easy decluttering tips you can apply to every space this winter, and more!

Listen to the Episode

Apple · Spotify · Patreon

Discussed in This Episode

  • How can we justify making time for seemingly frivolous pursuits?
  • Solve this equation: X is so important to me that I…

Source https://www.theminimalists.com/p513/

The Minimalists talk about making time for frivolous pursuits, what we’re willing to sacrifice for the important things, clutter that shows up unexpectedly, five easy decluttering tips you can apply to every space this winter, and more!

Listen to the Episode

Apple · Spotify · Patreon

Discussed in This Episode

  • How can we justify making time for seemingly frivolous pursuits?
  • Solve this equation: X is so important to me that I…

5 Easy Decluttering Tips You Can Apply to Every Space This Winter

Source https://www.theminimalists.com/winter/

The Minimalists discuss five decluttering tips to help get you prepared for winter.

How do you prepare for winter? Let us know in the YouTube comments.

The post 5 Easy Decluttering Tips You Can Apply to Every Space This Winter appeared first on The Minimalists.

Source https://www.theminimalists.com/winter/

The Minimalists discuss five decluttering tips to help get you prepared for winter.

How do you prepare for winter? Let us know in the YouTube comments.

The post 5 Easy Decluttering Tips You Can Apply to Every Space This Winter appeared first on The Minimalists.

Manufacturing Advances are Key to the Further Development of Extracellular Vesicle Therapies

Source https://www.fightaging.org/archives/2025/11/manufacturing-advances-are-key-to-the-further-development-of-extracellular-vesicle-therapies/

Stem cell therapies have existed for a few decades now, and over that time have moved from experimental use for many conditions in the medical tourism industry to a much more formulaic, controlled use for some conditions in the more regulated markets such as the US and Europe. More experimental use in medical tourism never went away, however. It became a larger industry, more varied, the body of knowledge more widespread, but the existence of a very formalized, robust set of procedures adopted by clinics and companies in more regulated markets where every therapy and its method of manufacture is reviewed in great detail (and consequently at great expense) doesn’t make the earlier, less costly, less certain approach go away. Well informed patients continue to have the choice over how they proceed.

The trajectory of the stem cell therapy field is pr…

Source https://www.fightaging.org/archives/2025/11/manufacturing-advances-are-key-to-the-further-development-of-extracellular-vesicle-therapies/

Stem cell therapies have existed for a few decades now, and over that time have moved from experimental use for many conditions in the medical tourism industry to a much more formulaic, controlled use for some conditions in the more regulated markets such as the US and Europe. More experimental use in medical tourism never went away, however. It became a larger industry, more varied, the body of knowledge more widespread, but the existence of a very formalized, robust set of procedures adopted by clinics and companies in more regulated markets where every therapy and its method of manufacture is reviewed in great detail (and consequently at great expense) doesn’t make the earlier, less costly, less certain approach go away. Well informed patients continue to have the choice over how they proceed.

The trajectory of the stem cell therapy field is pr…

When the Person You Love Is Disappearing into Addiction

Source https://tinybuddha.com/blog/when-the-person-you-love-is-disappearing-into-addiction/

“Boundaries are the distance at which I can love you and myself at the same time.” ~Prentis Hemphill

I thought I had seen the worst of it. I thought I knew what it meant to watch someone you love disappear into addiction. My mother taught me that lesson long before I was old enough to truly understand it.

Growing up, I saw her sink deep into heroin. I learned to read the signs before she even spoke. I knew when she was high. I knew when she was lying. I knew when she was gone, even when she was sitting right in front of me. And there was nothing I could do to stop it. I was just a child, powerless in the shadow of a disease that stole her piece by piece.<…

Source https://tinybuddha.com/blog/when-the-person-you-love-is-disappearing-into-addiction/

“Boundaries are the distance at which I can love you and myself at the same time.” ~Prentis Hemphill

I thought I had seen the worst of it. I thought I knew what it meant to watch someone you love disappear into addiction. My mother taught me that lesson long before I was old enough to truly understand it.

Growing up, I saw her sink deep into heroin. I learned to read the signs before she even spoke. I knew when she was high. I knew when she was lying. I knew when she was gone, even when she was sitting right in front of me. And there was nothing I could do to stop it. I was just a child, powerless in the shadow of a disease that stole her piece by piece.<…

Progress Towards a Viable Heat Treatment for Dry Macular Degeneration

Source https://www.fightaging.org/archives/2025/11/progress-towards-a-viable-heat-treatment-for-dry-macular-degeneration/

Macular degeneration is a progressive blindness caused by forms of age-related damage that disable and destroy cells of the retina, such as the accumulation of persistent forms of metabolic waste. The dry variant of macular degeneration, in which there is no great degree of inappropriate blood vessel growth in the retina, has no effective treatment at the present time – and treatments for the wet form typically only slow progression. The materials noted here discuss progress towards a precision heat therapy that uses a laser to induce mild cell stress and consequently greater cell maintenance activities in retinal tissue. If used in the early stages of the condition, animal studies suggest it can significantly postpone the onset of more severe degeneration.

The new heat treatment involves heating the <a href="https://en.wikipedia.org/wi…

Source https://www.fightaging.org/archives/2025/11/progress-towards-a-viable-heat-treatment-for-dry-macular-degeneration/

Macular degeneration is a progressive blindness caused by forms of age-related damage that disable and destroy cells of the retina, such as the accumulation of persistent forms of metabolic waste. The dry variant of macular degeneration, in which there is no great degree of inappropriate blood vessel growth in the retina, has no effective treatment at the present time – and treatments for the wet form typically only slow progression. The materials noted here discuss progress towards a precision heat therapy that uses a laser to induce mild cell stress and consequently greater cell maintenance activities in retinal tissue. If used in the early stages of the condition, animal studies suggest it can significantly postpone the onset of more severe degeneration.

The new heat treatment involves heating the <a href="https://en.wikipedia.org/wi…

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