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5 Easy Decluttering Tips You Can Apply to Every Space This Winter

Source https://www.theminimalists.com/winter/

The Minimalists discuss five decluttering tips to help get you prepared for winter.

How do you prepare for winter? Let us know in the YouTube comments.

The post 5 Easy Decluttering Tips You Can Apply to Every Space This Winter appeared first on The Minimalists.

Source https://www.theminimalists.com/winter/

The Minimalists discuss five decluttering tips to help get you prepared for winter.

How do you prepare for winter? Let us know in the YouTube comments.

The post 5 Easy Decluttering Tips You Can Apply to Every Space This Winter appeared first on The Minimalists.

Manufacturing Advances are Key to the Further Development of Extracellular Vesicle Therapies

Source https://www.fightaging.org/archives/2025/11/manufacturing-advances-are-key-to-the-further-development-of-extracellular-vesicle-therapies/

Stem cell therapies have existed for a few decades now, and over that time have moved from experimental use for many conditions in the medical tourism industry to a much more formulaic, controlled use for some conditions in the more regulated markets such as the US and Europe. More experimental use in medical tourism never went away, however. It became a larger industry, more varied, the body of knowledge more widespread, but the existence of a very formalized, robust set of procedures adopted by clinics and companies in more regulated markets where every therapy and its method of manufacture is reviewed in great detail (and consequently at great expense) doesn’t make the earlier, less costly, less certain approach go away. Well informed patients continue to have the choice over how they proceed.

The trajectory of the stem cell therapy field is pr…

Source https://www.fightaging.org/archives/2025/11/manufacturing-advances-are-key-to-the-further-development-of-extracellular-vesicle-therapies/

Stem cell therapies have existed for a few decades now, and over that time have moved from experimental use for many conditions in the medical tourism industry to a much more formulaic, controlled use for some conditions in the more regulated markets such as the US and Europe. More experimental use in medical tourism never went away, however. It became a larger industry, more varied, the body of knowledge more widespread, but the existence of a very formalized, robust set of procedures adopted by clinics and companies in more regulated markets where every therapy and its method of manufacture is reviewed in great detail (and consequently at great expense) doesn’t make the earlier, less costly, less certain approach go away. Well informed patients continue to have the choice over how they proceed.

The trajectory of the stem cell therapy field is pr…

When the Person You Love Is Disappearing into Addiction

Source https://tinybuddha.com/blog/when-the-person-you-love-is-disappearing-into-addiction/

“Boundaries are the distance at which I can love you and myself at the same time.” ~Prentis Hemphill

I thought I had seen the worst of it. I thought I knew what it meant to watch someone you love disappear into addiction. My mother taught me that lesson long before I was old enough to truly understand it.

Growing up, I saw her sink deep into heroin. I learned to read the signs before she even spoke. I knew when she was high. I knew when she was lying. I knew when she was gone, even when she was sitting right in front of me. And there was nothing I could do to stop it. I was just a child, powerless in the shadow of a disease that stole her piece by piece.<…

Source https://tinybuddha.com/blog/when-the-person-you-love-is-disappearing-into-addiction/

“Boundaries are the distance at which I can love you and myself at the same time.” ~Prentis Hemphill

I thought I had seen the worst of it. I thought I knew what it meant to watch someone you love disappear into addiction. My mother taught me that lesson long before I was old enough to truly understand it.

Growing up, I saw her sink deep into heroin. I learned to read the signs before she even spoke. I knew when she was high. I knew when she was lying. I knew when she was gone, even when she was sitting right in front of me. And there was nothing I could do to stop it. I was just a child, powerless in the shadow of a disease that stole her piece by piece.<…

Progress Towards a Viable Heat Treatment for Dry Macular Degeneration

Source https://www.fightaging.org/archives/2025/11/progress-towards-a-viable-heat-treatment-for-dry-macular-degeneration/

Macular degeneration is a progressive blindness caused by forms of age-related damage that disable and destroy cells of the retina, such as the accumulation of persistent forms of metabolic waste. The dry variant of macular degeneration, in which there is no great degree of inappropriate blood vessel growth in the retina, has no effective treatment at the present time – and treatments for the wet form typically only slow progression. The materials noted here discuss progress towards a precision heat therapy that uses a laser to induce mild cell stress and consequently greater cell maintenance activities in retinal tissue. If used in the early stages of the condition, animal studies suggest it can significantly postpone the onset of more severe degeneration.

The new heat treatment involves heating the <a href="https://en.wikipedia.org/wi…

Source https://www.fightaging.org/archives/2025/11/progress-towards-a-viable-heat-treatment-for-dry-macular-degeneration/

Macular degeneration is a progressive blindness caused by forms of age-related damage that disable and destroy cells of the retina, such as the accumulation of persistent forms of metabolic waste. The dry variant of macular degeneration, in which there is no great degree of inappropriate blood vessel growth in the retina, has no effective treatment at the present time – and treatments for the wet form typically only slow progression. The materials noted here discuss progress towards a precision heat therapy that uses a laser to induce mild cell stress and consequently greater cell maintenance activities in retinal tissue. If used in the early stages of the condition, animal studies suggest it can significantly postpone the onset of more severe degeneration.

The new heat treatment involves heating the <a href="https://en.wikipedia.org/wi…

Cranberry Orange Cookie Bars (Vegan + Gluten-Free)

Source https://minimalistbaker.com/cranberry-orange-cookie-bars/

Cranberry Orange Cookie Bars (Vegan + Gluten-Free)

The texture and flavor of a cookie with the ease of a bar? Talk about the perfect dessert! Introducing: cranberry orange cookie bars! 

These chewy, buttery cookie bars are packed with zesty orange flavor and pops of tart cranberries. Your new go-to treat awaits with just 1 bowl and 8 ingredients required! Did we mention they’re vegan and gluten-free? No one else has to know.

Cranberry Orange Cookie Bars (Vegan + Gluten-Free) from Minimalist Baker →

Source https://minimalistbaker.com/cranberry-orange-cookie-bars/

Cranberry Orange Cookie Bars (Vegan + Gluten-Free)

The texture and flavor of a cookie with the ease of a bar? Talk about the perfect dessert! Introducing: cranberry orange cookie bars! 

These chewy, buttery cookie bars are packed with zesty orange flavor and pops of tart cranberries. Your new go-to treat awaits with just 1 bowl and 8 ingredients required! Did we mention they’re vegan and gluten-free? No one else has to know.

Cranberry Orange Cookie Bars (Vegan + Gluten-Free) from Minimalist Baker →

The Invisible Prison Shyness Builds and What Helped Me Walk Free

Source https://tinybuddha.com/blog/the-invisible-prison-shyness-builds-and-what-helped-me-walk-free/

“Life shrinks or expands in proportion to one’s courage.” ~Anaïs Nin

When I think back on my life, shyness feels like an inner prison I carried with me for years. Not a prison with bars and guards, but a quieter kind—made of hesitation, fear, and silence. It kept me standing still while life moved forward around me.

One memory stays with me: my eighth-grade dance. The gym was alive with music, kids moving awkwardly but freely on the floor, laughing, bumping into one another, having fun. And there I was in the corner, figuratively stomping paper cups.

That’s how I remember it—like I was crushing cardboard instead of stepping into life. I can even smile at t…

Source https://tinybuddha.com/blog/the-invisible-prison-shyness-builds-and-what-helped-me-walk-free/

“Life shrinks or expands in proportion to one’s courage.” ~Anaïs Nin

When I think back on my life, shyness feels like an inner prison I carried with me for years. Not a prison with bars and guards, but a quieter kind—made of hesitation, fear, and silence. It kept me standing still while life moved forward around me.

One memory stays with me: my eighth-grade dance. The gym was alive with music, kids moving awkwardly but freely on the floor, laughing, bumping into one another, having fun. And there I was in the corner, figuratively stomping paper cups.

That’s how I remember it—like I was crushing cardboard instead of stepping into life. I can even smile at t…

Glial Cell Dysfunction, Both Cause and Consequence of Brain Aging

Source https://www.fightaging.org/archives/2025/11/glial-cell-dysfunction-both-cause-and-consequence-of-brain-aging/

The broad category of glial cell includes all of the cells making up the nervous system that are not neurons. This includes the innate immune cells known as microglia, the astrocytes that manage brain metabolism and make up much of the brain’s structure, the oligodendrocytes that maintain the myelin sheathing necessary for nerves to conduct electrical impulses, and a few other smaller or more localized populations. These are all very different cell types with very different functions, so…

Source https://www.fightaging.org/archives/2025/11/glial-cell-dysfunction-both-cause-and-consequence-of-brain-aging/

The broad category of glial cell includes all of the cells making up the nervous system that are not neurons. This includes the innate immune cells known as microglia, the astrocytes that manage brain metabolism and make up much of the brain’s structure, the oligodendrocytes that maintain the myelin sheathing necessary for nerves to conduct electrical impulses, and a few other smaller or more localized populations. These are all very different cell types with very different functions, so…

Medicare Update

Source https://seniorplanet.org/articles-medicare-update/

Expect changes in Medicare this year – higher drug prices, higher co-pays, and doctors and hospitals dropping from Medicare Advantage plans.

The post Medicare Update appeared first on Senior Planet from AARP.

Source https://seniorplanet.org/articles-medicare-update/

Expect changes in Medicare this year – higher drug prices, higher co-pays, and doctors and hospitals dropping from Medicare Advantage plans.

The post Medicare Update appeared first on Senior Planet from AARP.

Aging of the Gut Microbiome as a Contribution to Inflammation and Neurodegeneration

Source https://www.fightaging.org/archives/2025/11/aging-of-the-gut-microbiome-as-a-contribution-to-inflammation-and-neurodegeneration/

Here find a review of what is known of the ways in which age-related changes in the gut microbiome can contribute to the chronic inflammation of aging and development of neurodegenerative conditions. The ability to accurately map the composition of the gut microbiome by sequencing microbial DNA, in particular species-specific variations in the 16S rRNA gene, has produced a vast and growing body of data. Researchers have linked specific microbial populations to specific age-related conditions, and shown that the balance of populations …

Source https://www.fightaging.org/archives/2025/11/aging-of-the-gut-microbiome-as-a-contribution-to-inflammation-and-neurodegeneration/

Here find a review of what is known of the ways in which age-related changes in the gut microbiome can contribute to the chronic inflammation of aging and development of neurodegenerative conditions. The ability to accurately map the composition of the gut microbiome by sequencing microbial DNA, in particular species-specific variations in the 16S rRNA gene, has produced a vast and growing body of data. Researchers have linked specific microbial populations to specific age-related conditions, and shown that the balance of populations …

A Profile of Sirtuins 1, 3, and 6 in Aging Humans

Source https://www.fightaging.org/archives/2025/11/a-profile-of-sirtuins-1-3-and-6-in-aging-humans/

Sirtuins are involved in the regulation of metabolism in various ways, and are clearly quite important to cell function as their structure is very similar in species as divergent as yeast, flies, and humans. Sirtuin 1 as a target for interventions in aging was intensely overhyped and likely not actually very useful in a practical sense. Sirtuin 3 is more interesting, based on research suggesting that it could have calorie restriction mimetic effects, and is <a href="https://www.fightaging.org/archives/2025/08/reviewing-what…

Source https://www.fightaging.org/archives/2025/11/a-profile-of-sirtuins-1-3-and-6-in-aging-humans/

Sirtuins are involved in the regulation of metabolism in various ways, and are clearly quite important to cell function as their structure is very similar in species as divergent as yeast, flies, and humans. Sirtuin 1 as a target for interventions in aging was intensely overhyped and likely not actually very useful in a practical sense. Sirtuin 3 is more interesting, based on research suggesting that it could have calorie restriction mimetic effects, and is <a href="https://www.fightaging.org/archives/2025/08/reviewing-what…

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