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Play November: Spark Creative Paths

Source https://seniorplanet.org/play-november-spark-creative-paths/

Put your creative mind to the test! This month’s puzzle, Spark Creative Paths, invites you to explore new ideas and playful possibilities.

The post Play November: Spark Creative Paths appeared first on Senior Planet from AARP.

Source https://seniorplanet.org/play-november-spark-creative-paths/

Put your creative mind to the test! This month’s puzzle, Spark Creative Paths, invites you to explore new ideas and playful possibilities.

The post Play November: Spark Creative Paths appeared first on Senior Planet from AARP.

Fight Aging! Newsletter, November 10th 2025

Source https://www.fightaging.org/archives/2025/11/fight-aging-newsletter-november-10th-2025/

Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe to the newsletter,
please visit:
https://www.fightaging.org/newsletter/.
To unsubscribe, send email or reply to this email at newsletter@fightaging.org with “unsubscribe” in the subject or body.

Longevity Industry Consulting Services

Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out more: https://www.fightaging.org/services/

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Source https://www.fightaging.org/archives/2025/11/fight-aging-newsletter-november-10th-2025/

Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe to the newsletter,
please visit:
https://www.fightaging.org/newsletter/.
To unsubscribe, send email or reply to this email at newsletter@fightaging.org with “unsubscribe” in the subject or body.

Longevity Industry Consulting Services

Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out more: https://www.fightaging.org/services/

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Is Herpes Simplex Virus Type 1 an Important Contribution to Alzheimer's Disease Risk?

Source https://www.fightaging.org/archives/2025/11/is-herpes-simplex-virus-type-1-an-important-contribution-to-alzheimers-disease-risk/

A growing body of literature is associated with the debate over whether persistent viral infection provides a significant contribution to Alzheimer’s disease and other neurodegenerative conditions. Some viruses, such as varieties of herpes simplex virus (HSV), cannot be effectively cleared by the immune system. They linger in the body to continually provoke immune reactions. The contribution of viral infection is clearly not reliable and sizable, however, as the epidemiological evidence is mixed. Some study populations show a correlation between infection status…

Source https://www.fightaging.org/archives/2025/11/is-herpes-simplex-virus-type-1-an-important-contribution-to-alzheimers-disease-risk/

A growing body of literature is associated with the debate over whether persistent viral infection provides a significant contribution to Alzheimer’s disease and other neurodegenerative conditions. Some viruses, such as varieties of herpes simplex virus (HSV), cannot be effectively cleared by the immune system. They linger in the body to continually provoke immune reactions. The contribution of viral infection is clearly not reliable and sizable, however, as the epidemiological evidence is mixed. Some study populations show a correlation between infection status…

Make Procrastination Your Friend

Source https://www.theminimalists.com/friend/

T.K. Coleman talks about how to stop putting things off.

What are you putting off right now? Let us know in the YouTube comments.

The post Make Procrastination Your Friend appeared first on The Minimalists.

Source https://www.theminimalists.com/friend/

T.K. Coleman talks about how to stop putting things off.

What are you putting off right now? Let us know in the YouTube comments.

The post Make Procrastination Your Friend appeared first on The Minimalists.

Inflammation and Maladaptive Extracellular Matrix Remodeling in the Aging Heart

Source https://www.fightaging.org/archives/2025/11/inflammation-and-maladaptive-extracellular-matrix-remodeling-in-the-aging-heart/

Fibrosis is a feature of aging, in which the normal processes of tissue maintenance run awry and scar-like structures form to disrupt tissue structure and function. The proximate cause is altered behavior on the part of fibroblast cells that largely responsible for maintenance of the extracellular matrix. After than, one can point to the continual inflammatory signaling that takes place in aged tissue, and disrupts many forms of cell activity, not just this one. As is usually the case in matters relating to aging, a more comprehensive picture of causes and consequences leading to inflammation and altered fibroblast behavior, one that encompasses all of the mechanisms involved and their various layers and interactions, has yet to emerge. Biochemistry is exceedingly complex.

Cardiov…

Source https://www.fightaging.org/archives/2025/11/inflammation-and-maladaptive-extracellular-matrix-remodeling-in-the-aging-heart/

Fibrosis is a feature of aging, in which the normal processes of tissue maintenance run awry and scar-like structures form to disrupt tissue structure and function. The proximate cause is altered behavior on the part of fibroblast cells that largely responsible for maintenance of the extracellular matrix. After than, one can point to the continual inflammatory signaling that takes place in aged tissue, and disrupts many forms of cell activity, not just this one. As is usually the case in matters relating to aging, a more comprehensive picture of causes and consequences leading to inflammation and altered fibroblast behavior, one that encompasses all of the mechanisms involved and their various layers and interactions, has yet to emerge. Biochemistry is exceedingly complex.

Cardiov…

Persistent Infection Correlations with Increased Risk of Cardiovascular Disease

Source https://www.fightaging.org/archives/2025/11/persistent-infection-correlations-with-increased-risk-of-cardiovascular-disease/

There is considerable debate over the degree to which persistent viral infections contribute to neurodegenerative conditions such as Alzheimer’s disease. If persistent viral infection causes generalized pathology over time, such as via increased chronic inflammation in later life, one would expect it to increase the incidence and severity of most age-related conditions. With that in mind, researchers here analyze a sizable body of study data to quantify the correlations between viral infection and cardiovascular disease. As one might expect, the results suggest that better control of viral infection could improve late life health.

It is well recognized t…

Source https://www.fightaging.org/archives/2025/11/persistent-infection-correlations-with-increased-risk-of-cardiovascular-disease/

There is considerable debate over the degree to which persistent viral infections contribute to neurodegenerative conditions such as Alzheimer’s disease. If persistent viral infection causes generalized pathology over time, such as via increased chronic inflammation in later life, one would expect it to increase the incidence and severity of most age-related conditions. With that in mind, researchers here analyze a sizable body of study data to quantify the correlations between viral infection and cardiovascular disease. As one might expect, the results suggest that better control of viral infection could improve late life health.

It is well recognized t…

Results from a Human Trial of Magnetic Mitohormesis

Source https://www.fightaging.org/archives/2025/11/results-from-a-human-trial-of-magnetic-mitohormesis/

The use of electromagnetic fields to manipulate cellular biochemistry in favorable ways is a field very much in its infancy in comparison to the well established use of small molecule drugs. At the high level, it is quite similar to exploration with small molecules, in that there is a great deal of freedom to experiment with parameters: intensity, frequency, duration, dosing, a focus on primarily electrical versus primarily magnetic fields, equipment differences, and so forth. Within that vast parameter space, only some combinations will be useful. In general this part of the field is characterized by results that fail to replicate and incomplete information on all of the parameters needed to recreate the exact protocol used. Nonetheless, there are some areas of promise where multiple research groups have achieved positive results, and even brought the work …

Source https://www.fightaging.org/archives/2025/11/results-from-a-human-trial-of-magnetic-mitohormesis/

The use of electromagnetic fields to manipulate cellular biochemistry in favorable ways is a field very much in its infancy in comparison to the well established use of small molecule drugs. At the high level, it is quite similar to exploration with small molecules, in that there is a great deal of freedom to experiment with parameters: intensity, frequency, duration, dosing, a focus on primarily electrical versus primarily magnetic fields, equipment differences, and so forth. Within that vast parameter space, only some combinations will be useful. In general this part of the field is characterized by results that fail to replicate and incomplete information on all of the parameters needed to recreate the exact protocol used. Nonetheless, there are some areas of promise where multiple research groups have achieved positive results, and even brought the work …

JFM’s Favorite Albums of 2024

Source https://www.theminimalists.com/albums2024/

By Joshua Fields Millburn

Each year since we started The Minimalists, I’ve catalogued my favorite albums at the end of the calendar year. This one is a few months late, but better late than never. Here are my favorites from 2024. (You can find previous years here.)

1. Donovan Woods, Things Were Never Good If They’re Not Good Now

2. Joshua Hyslop, Evergold

3. Soccer Mommy, Evergreen

4. Mat Kearney, Mat …

Source https://www.theminimalists.com/albums2024/

By Joshua Fields Millburn

Each year since we started The Minimalists, I’ve catalogued my favorite albums at the end of the calendar year. This one is a few months late, but better late than never. Here are my favorites from 2024. (You can find previous years here.)

1. Donovan Woods, Things Were Never Good If They’re Not Good Now

2. Joshua Hyslop, Evergold

3. Soccer Mommy, Evergreen

4. Mat Kearney, Mat …

Meet the Trainer: David Slapak

Source https://seniorplanet.org/articles-meet-trainer-miami/

Before joining the Senior Planet Miami as a technology trainer, David taught English as a second language in South Korea and Turkey. 

The post Meet the Trainer: David Slapak appeared first on Senior Planet from AARP.

Source https://seniorplanet.org/articles-meet-trainer-miami/

Before joining the Senior Planet Miami as a technology trainer, David taught English as a second language in South Korea and Turkey. 

The post Meet the Trainer: David Slapak appeared first on Senior Planet from AARP.

Meet the Panelists of Senior Planet’s Caregiving Panel 

Source https://seniorplanet.org/articles-panelists-caregiving/

For National Caregiving Month, Senior Planet will host a informative and insightful Zoom panel discussion on Friday, November 14 at 2pm ET. 

The post Meet the Panelists of Senior Planet’s Caregiving Panel  appeared first on Senior Planet from AARP.

Source https://seniorplanet.org/articles-panelists-caregiving/

For National Caregiving Month, Senior Planet will host a informative and insightful Zoom panel discussion on Friday, November 14 at 2pm ET. 

The post Meet the Panelists of Senior Planet’s Caregiving Panel  appeared first on Senior Planet from AARP.

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