Source https://www.theminimalists.com/p511/
The Minimalists speak with Ryan Holiday about how the stoics dealt with sentimental items, the potential virtue of holding on, stoical insights about values, regrets, mental clutter, seven things minimalists would never put in their living room, and much more.
Listen to the Episode
Apple · Spotify · Patreon
Discussed in This Episode
- How would the stoics have handled their sentimental items?
- When is it virtuous to hold on?</sp…
Source https://www.theminimalists.com/p511/
The Minimalists speak with Ryan Holiday about how the stoics dealt with sentimental items, the potential virtue of holding on, stoical insights about values, regrets, mental clutter, seven things minimalists would never put in their living room, and much more.
Listen to the Episode
Apple · Spotify · Patreon
Discussed in This Episode
- How would the stoics have handled their sentimental items?
- When is it virtuous to hold on?</sp…
Source https://www.fightaging.org/archives/2025/10/fight-aging-newsletter-october-27th-2025/
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe to the newsletter,
please visit:
https://www.fightaging.org/newsletter/.
To unsubscribe, send email or reply to this email at newsletter@fightaging.org with “unsubscribe” in the subject or body.
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out more: https://www.fightaging.org/services/
<a name="t…
Source https://www.fightaging.org/archives/2025/10/fight-aging-newsletter-october-27th-2025/
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe to the newsletter,
please visit:
https://www.fightaging.org/newsletter/.
To unsubscribe, send email or reply to this email at newsletter@fightaging.org with “unsubscribe” in the subject or body.
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out more: https://www.fightaging.org/services/
<a name="t…
Source https://www.theminimalists.com/shutup/
T.K. Coleman talks about how to get unstuck from conversations that make you feel trapped.
What was the last conversation you felt trapped in? Let us know in the YouTube comments.
Subscribe to The Minimalists via
email.
The post How to Tell People to Shut Up appeared first on The Minimalists.
…
Source https://www.theminimalists.com/shutup/
T.K. Coleman talks about how to get unstuck from conversations that make you feel trapped.
What was the last conversation you felt trapped in? Let us know in the YouTube comments.
Subscribe to The Minimalists via
email.
The post How to Tell People to Shut Up appeared first on The Minimalists.
…
Source https://www.fightaging.org/archives/2025/10/towards-engineered-mitochondria-for-therapy/
Cells can take up mitochondria from the surrounding environment, and researchers have demonstrated in mice that intravenous delivery of mitochondria allows some degree of replacement of the native populations in cells. This improves function when native mitochondria are dysfunctional, as occurs with age. At present, delivery of mitochondria as a therapy to restore mitochondrial function in older people is a work in progress. A few companies are working on the challenge, which largely involves developing the techniques needed to reliably manufacture mitochondria at scale. In this paper, researchers look beyond that effort to the next step in the road, which is to engineer the delivered mitochondria to be more efficient and more resilient, or to act as factories for therapeutic molecules, or to have some other desired capability.
Conventional mi…
Source https://www.fightaging.org/archives/2025/10/towards-engineered-mitochondria-for-therapy/
Cells can take up mitochondria from the surrounding environment, and researchers have demonstrated in mice that intravenous delivery of mitochondria allows some degree of replacement of the native populations in cells. This improves function when native mitochondria are dysfunctional, as occurs with age. At present, delivery of mitochondria as a therapy to restore mitochondrial function in older people is a work in progress. A few companies are working on the challenge, which largely involves developing the techniques needed to reliably manufacture mitochondria at scale. In this paper, researchers look beyond that effort to the next step in the road, which is to engineer the delivered mitochondria to be more efficient and more resilient, or to act as factories for therapeutic molecules, or to have some other desired capability.
Conventional mi…
Source https://www.fightaging.org/archives/2025/10/reviewing-the-ongoing-move-from-stem-cell-therapies-to-exosome-therapies/
The medical tourism industry has adopted the therapeutic use of exosomes derived from stem cells in much the same way as it adopted the use of stem cell therapies. Transplanted stem cells produce benefits via signaling, and most signaling is carried via extracellular vesicles such as exosomes. From a logistics point of view, exosomes are more easily stored, transported, and used, while all of the tools needed to harvest exosomes from stem cell cultures already existed. Meanwhile, the regulated medical industry lags years behind, given the large costs and lengthy development programs required to satisfy regulator…
Source https://www.fightaging.org/archives/2025/10/reviewing-the-ongoing-move-from-stem-cell-therapies-to-exosome-therapies/
The medical tourism industry has adopted the therapeutic use of exosomes derived from stem cells in much the same way as it adopted the use of stem cell therapies. Transplanted stem cells produce benefits via signaling, and most signaling is carried via extracellular vesicles such as exosomes. From a logistics point of view, exosomes are more easily stored, transported, and used, while all of the tools needed to harvest exosomes from stem cell cultures already existed. Meanwhile, the regulated medical industry lags years behind, given the large costs and lengthy development programs required to satisfy regulator…