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Senior Planet Book Club: Love, Chai, and Other Four-Letter Words by Annika Sharma

Source https://seniorplanet.org/articles-senior-planet-book-club-love-chai-and-other-four-letter-words-by-annika-sharma/

Join our book club and enjoy November’s reading selection! View this week’s assignment, and let us know what you think in the comments.

The post Senior Planet Book Club: <em>Love, Chai, and Other Four-Letter Words</em> by Annika Sharma appeared first on Senior Planet from AARP.

Source https://seniorplanet.org/articles-senior-planet-book-club-love-chai-and-other-four-letter-words-by-annika-sharma/

Join our book club and enjoy November’s reading selection! View this week’s assignment, and let us know what you think in the comments.

The post Senior Planet Book Club: <em>Love, Chai, and Other Four-Letter Words</em> by Annika Sharma appeared first on Senior Planet from AARP.

7 Things Minimalists Would Never Put in Their Living Room

Source https://www.theminimalists.com/furniture/

The Minimalists speak with Ryan Holiday about items that don’t belong in a minimalist living room.

What’s your favorite item in your living room? Let us know in the YouTube comments.

The post 7 Things Minimalists Would Never Put in Their Living Room appeared first on The Minimalists.

Source https://www.theminimalists.com/furniture/

The Minimalists speak with Ryan Holiday about items that don’t belong in a minimalist living room.

What’s your favorite item in your living room? Let us know in the YouTube comments.

The post 7 Things Minimalists Would Never Put in Their Living Room appeared first on The Minimalists.

The Man Cave on…Retirement and Significant Others

Source https://seniorplanet.org/articles-mancave-retirement-sos/

Are conflicts that arise in retirement fueling the rise in “Grey Divorce?” Handling the change in relationship dynamics is key to happy coupledom.

The post The Man Cave on…Retirement and Significant Others appeared first on Senior Planet from AARP.

Source https://seniorplanet.org/articles-mancave-retirement-sos/

Are conflicts that arise in retirement fueling the rise in “Grey Divorce?” Handling the change in relationship dynamics is key to happy coupledom.

The post The Man Cave on…Retirement and Significant Others appeared first on Senior Planet from AARP.

Get Social – and Mentor!

Source https://seniorplanet.org/articles-get-social-and-mentor/

Is mentorship right for you – and are you right for it? Experts and mentors share stories, insights and practical tips on this fulfilling social activity. 

The post Get Social – and Mentor! appeared first on Senior Planet from AARP.

Source https://seniorplanet.org/articles-get-social-and-mentor/

Is mentorship right for you – and are you right for it? Experts and mentors share stories, insights and practical tips on this fulfilling social activity. 

The post Get Social – and Mentor! appeared first on Senior Planet from AARP.

Centenarians Exhibit Modestly Greater Genetic Protection from Alzheimer's Disease

Source https://www.fightaging.org/archives/2025/10/centenarians-exhibit-modestly-greater-genetic-protection-from-alzheimers-disease/

The low (and still falling) cost of modern omics technologies ensure that databases of genetic information are expanding at a fast pace. Researchers who study aging have amassed a wealth of information on the biochemistry of people at various ages, but considerable focus has been placed on the genetics of extremely old individuals. The hope has always been to identify particular genes or protein interactions or other aspects of cellular biochemistry that are meaningfully protective, and thus could serve as a starting point for the development of therapies that will slow aging.

Unfortunately what has emerged from this research is (a) the likelihood that previous estimates of the contribution of genetic variants to life expectancy were too high, (b) that ve…

Source https://www.fightaging.org/archives/2025/10/centenarians-exhibit-modestly-greater-genetic-protection-from-alzheimers-disease/

The low (and still falling) cost of modern omics technologies ensure that databases of genetic information are expanding at a fast pace. Researchers who study aging have amassed a wealth of information on the biochemistry of people at various ages, but considerable focus has been placed on the genetics of extremely old individuals. The hope has always been to identify particular genes or protein interactions or other aspects of cellular biochemistry that are meaningfully protective, and thus could serve as a starting point for the development of therapies that will slow aging.

Unfortunately what has emerged from this research is (a) the likelihood that previous estimates of the contribution of genetic variants to life expectancy were too high, (b) that ve…

Podcast Ep. 511 | Holding On

Source https://www.theminimalists.com/p511/

The Minimalists speak with Ryan Holiday about how the stoics dealt with sentimental items, the potential virtue of holding on, stoical insights about values, regrets, mental clutter, seven things minimalists would never put in their living room, and much more.

Listen to the Episode

Apple · Spotify · Patreon

Discussed in This Episode

  • How would the stoics have handled their sentimental items?
  • When is it virtuous to hold on?</sp…

Source https://www.theminimalists.com/p511/

The Minimalists speak with Ryan Holiday about how the stoics dealt with sentimental items, the potential virtue of holding on, stoical insights about values, regrets, mental clutter, seven things minimalists would never put in their living room, and much more.

Listen to the Episode

Apple · Spotify · Patreon

Discussed in This Episode

  • How would the stoics have handled their sentimental items?
  • When is it virtuous to hold on?</sp…

Fight Aging! Newsletter, October 27th 2025

Source https://www.fightaging.org/archives/2025/10/fight-aging-newsletter-october-27th-2025/

Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe to the newsletter,
please visit:
https://www.fightaging.org/newsletter/.
To unsubscribe, send email or reply to this email at newsletter@fightaging.org with “unsubscribe” in the subject or body.

Longevity Industry Consulting Services

Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out more: https://www.fightaging.org/services/

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Source https://www.fightaging.org/archives/2025/10/fight-aging-newsletter-october-27th-2025/

Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe to the newsletter,
please visit:
https://www.fightaging.org/newsletter/.
To unsubscribe, send email or reply to this email at newsletter@fightaging.org with “unsubscribe” in the subject or body.

Longevity Industry Consulting Services

Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out more: https://www.fightaging.org/services/

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How to Tell People to Shut Up

Source https://www.theminimalists.com/shutup/

T.K. Coleman talks about how to get unstuck from conversations that make you feel trapped.

What was the last conversation you felt trapped in? Let us know in the YouTube comments.

The post How to Tell People to Shut Up appeared first on The Minimalists.

Source https://www.theminimalists.com/shutup/

T.K. Coleman talks about how to get unstuck from conversations that make you feel trapped.

What was the last conversation you felt trapped in? Let us know in the YouTube comments.

The post How to Tell People to Shut Up appeared first on The Minimalists.

Towards Engineered Mitochondria for Therapy

Source https://www.fightaging.org/archives/2025/10/towards-engineered-mitochondria-for-therapy/

Cells can take up mitochondria from the surrounding environment, and researchers have demonstrated in mice that intravenous delivery of mitochondria allows some degree of replacement of the native populations in cells. This improves function when native mitochondria are dysfunctional, as occurs with age. At present, delivery of mitochondria as a therapy to restore mitochondrial function in older people is a work in progress. A few companies are working on the challenge, which largely involves developing the techniques needed to reliably manufacture mitochondria at scale. In this paper, researchers look beyond that effort to the next step in the road, which is to engineer the delivered mitochondria to be more efficient and more resilient, or to act as factories for therapeutic molecules, or to have some other desired capability.

Conventional mi…

Source https://www.fightaging.org/archives/2025/10/towards-engineered-mitochondria-for-therapy/

Cells can take up mitochondria from the surrounding environment, and researchers have demonstrated in mice that intravenous delivery of mitochondria allows some degree of replacement of the native populations in cells. This improves function when native mitochondria are dysfunctional, as occurs with age. At present, delivery of mitochondria as a therapy to restore mitochondrial function in older people is a work in progress. A few companies are working on the challenge, which largely involves developing the techniques needed to reliably manufacture mitochondria at scale. In this paper, researchers look beyond that effort to the next step in the road, which is to engineer the delivered mitochondria to be more efficient and more resilient, or to act as factories for therapeutic molecules, or to have some other desired capability.

Conventional mi…

Reviewing the Ongoing Move from Stem Cell Therapies to Exosome Therapies

Source https://www.fightaging.org/archives/2025/10/reviewing-the-ongoing-move-from-stem-cell-therapies-to-exosome-therapies/

The medical tourism industry has adopted the therapeutic use of exosomes derived from stem cells in much the same way as it adopted the use of stem cell therapies. Transplanted stem cells produce benefits via signaling, and most signaling is carried via extracellular vesicles such as exosomes. From a logistics point of view, exosomes are more easily stored, transported, and used, while all of the tools needed to harvest exosomes from stem cell cultures already existed. Meanwhile, the regulated medical industry lags years behind, given the large costs and lengthy development programs required to satisfy regulator…

Source https://www.fightaging.org/archives/2025/10/reviewing-the-ongoing-move-from-stem-cell-therapies-to-exosome-therapies/

The medical tourism industry has adopted the therapeutic use of exosomes derived from stem cells in much the same way as it adopted the use of stem cell therapies. Transplanted stem cells produce benefits via signaling, and most signaling is carried via extracellular vesicles such as exosomes. From a logistics point of view, exosomes are more easily stored, transported, and used, while all of the tools needed to harvest exosomes from stem cell cultures already existed. Meanwhile, the regulated medical industry lags years behind, given the large costs and lengthy development programs required to satisfy regulator…

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