Source https://www.theminimalists.com/spiral/
T.K. Coleman talks about how to get out of an argument spiral.
What was the subject of your last argument? Let us know in the YouTube comments.
Subscribe to The Minimalists via
email.
The post You’re Both Idiots! appeared first on The Minimalists.
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Source https://www.theminimalists.com/spiral/
T.K. Coleman talks about how to get out of an argument spiral.
What was the subject of your last argument? Let us know in the YouTube comments.
Subscribe to The Minimalists via
email.
The post You’re Both Idiots! appeared first on The Minimalists.
…
Source https://seniorplanet.org/articles-open-thread-penny-candy/
Goodbye Tootsie Rolls and Mary Janes! The end of the penny…and the end of penny candy.
The post Open Thread: The End of Penny Candy appeared first on Senior Planet from AARP.
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Source https://seniorplanet.org/articles-open-thread-penny-candy/
Goodbye Tootsie Rolls and Mary Janes! The end of the penny…and the end of penny candy.
The post Open Thread: The End of Penny Candy appeared first on Senior Planet from AARP.
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Source https://www.fightaging.org/archives/2025/11/nadp-in-the-cell-cytosol-influences-vascular-aging/
Nicotinamide adenine dinucleotide phosphate (NADP) has a different portfolio of functions in the cell to the better known nicotinamide adenine dinucleotide (NAD) that has been a focus for parts of the research community in recent years. NADP is thought to be primarily important as a defense against oxidative stress. Here, researchers discuss the role played by insufficient levels of NADP in vascular aging, finding that it encourages greater cellular senescence in the vascular endothelium, thus promoting endothelial dysfunction as a contribution to <a href="https://en.wikipe…
Source https://www.fightaging.org/archives/2025/11/nadp-in-the-cell-cytosol-influences-vascular-aging/
Nicotinamide adenine dinucleotide phosphate (NADP) has a different portfolio of functions in the cell to the better known nicotinamide adenine dinucleotide (NAD) that has been a focus for parts of the research community in recent years. NADP is thought to be primarily important as a defense against oxidative stress. Here, researchers discuss the role played by insufficient levels of NADP in vascular aging, finding that it encourages greater cellular senescence in the vascular endothelium, thus promoting endothelial dysfunction as a contribution to <a href="https://en.wikipe…
Source https://www.fightaging.org/archives/2025/11/the-endothelial-to-mesenchymal-transition-in-the-aging-of-the-brains-vasculature/
The aging of the blood vessels supplying the brain into a state of dysfunction provides an important contribution to the onset and progression of neurodegenerative conditions. There are many aspects to this vascular aging, including: loss of capillary density over time that reduces the ability of the vasculature to deliver sufficient nutrients to cells in brain tissue; the atherosclerosis that narrows and weakens major vessels with fatty deposits; the disruption of normal function of the endothelium, the inner layer of blood vessels; disruption of the normal function of the smooth muscle tha…
Source https://www.fightaging.org/archives/2025/11/the-endothelial-to-mesenchymal-transition-in-the-aging-of-the-brains-vasculature/
The aging of the blood vessels supplying the brain into a state of dysfunction provides an important contribution to the onset and progression of neurodegenerative conditions. There are many aspects to this vascular aging, including: loss of capillary density over time that reduces the ability of the vasculature to deliver sufficient nutrients to cells in brain tissue; the atherosclerosis that narrows and weakens major vessels with fatty deposits; the disruption of normal function of the endothelium, the inner layer of blood vessels; disruption of the normal function of the smooth muscle tha…
Source https://www.fightaging.org/archives/2025/11/elastin-like-recombinamers-enable-regrowth-of-damaged-enamel/
Provoking regrowth of tooth enamel by mimicking some of its structure appears to be a going concern in dental research, if judging from this paper and another similar approach using keratin. At the high level, the idea is to coat damaged enamel with material that encourages the chemical mineralization process that takes place during enamel formation. Interestingly, the specific molecular structures demonstrated here allow this process to take place even when applied to exposed dentin. We can hope that cavities and fillings will soon enough be a thing of the past.
Tooth enamel is characterised by an intricate hierarchical organization of <a href="http://en.wikipedia.org/wiki/A…
Source https://www.fightaging.org/archives/2025/11/elastin-like-recombinamers-enable-regrowth-of-damaged-enamel/
Provoking regrowth of tooth enamel by mimicking some of its structure appears to be a going concern in dental research, if judging from this paper and another similar approach using keratin. At the high level, the idea is to coat damaged enamel with material that encourages the chemical mineralization process that takes place during enamel formation. Interestingly, the specific molecular structures demonstrated here allow this process to take place even when applied to exposed dentin. We can hope that cavities and fillings will soon enough be a thing of the past.
Tooth enamel is characterised by an intricate hierarchical organization of <a href="http://en.wikipedia.org/wiki/A…
Source https://seniorplanet.org/articles-program-spotlight-book-club/
Love to read? Love to chat? Senior Planet’s book club brings people together to discuss a new book – chosen by Senior Planet participants – every month.
The post Program Spotlight: The Book Club appeared first on Senior Planet from AARP.
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Source https://seniorplanet.org/articles-program-spotlight-book-club/
Love to read? Love to chat? Senior Planet’s book club brings people together to discuss a new book – chosen by Senior Planet participants – every month.
The post Program Spotlight: The Book Club appeared first on Senior Planet from AARP.
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Source https://seniorplanet.org/articles-techspert-end-windows-10/
Microsoft has officially ended support for Windows 10 as of October 14, 2025. Learn what this means, how to stay secure, and what’s new in Windows 11.
The post Ask The Techspert: What the End of Windows 10 Means and What You Can Do About It appeared first on Senior Planet from AARP.
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Source https://seniorplanet.org/articles-techspert-end-windows-10/
Microsoft has officially ended support for Windows 10 as of October 14, 2025. Learn what this means, how to stay secure, and what’s new in Windows 11.
The post Ask The Techspert: What the End of Windows 10 Means and What You Can Do About It appeared first on Senior Planet from AARP.
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Source https://www.fightaging.org/archives/2025/11/high-cumulative-blood-pressure-correlates-with-a-sizable-increase-in-dementia-risk/
The raised blood pressure of hypertension is damaging to sensitive tissues throughout the body, but particularly the brain. Alongside many other issues in the health and function of the vascular system, hypertension increases the pace of rupture of tiny blood vessels in the brain, each such event destroying a small volume of brain tissue. Over time this adds up to degrade cognitive function and contribute to the development of outright dementia. Thus high blood pressure is harmful, and the longer the period of time in which blood pressure is elevated, the more harm is done. Here, researchers assess <a href="https://doi.org/10.1161/HYPE…
Source https://www.fightaging.org/archives/2025/11/high-cumulative-blood-pressure-correlates-with-a-sizable-increase-in-dementia-risk/
The raised blood pressure of hypertension is damaging to sensitive tissues throughout the body, but particularly the brain. Alongside many other issues in the health and function of the vascular system, hypertension increases the pace of rupture of tiny blood vessels in the brain, each such event destroying a small volume of brain tissue. Over time this adds up to degrade cognitive function and contribute to the development of outright dementia. Thus high blood pressure is harmful, and the longer the period of time in which blood pressure is elevated, the more harm is done. Here, researchers assess <a href="https://doi.org/10.1161/HYPE…
Source https://tinybuddha.com/blog/what-happened-when-i-stopped-expecting-perfection-from-myself/

“There is no amount of self-improvement that can make up for a lack of self-acceptance.” ~Robert Holden
Six years ago, I forgot it was picture day at my daughter’s school. She left the house in a sweatshirt with a faint, unidentifiable stain and hair still bent from yesterday’s ponytail.
The photographer probably spent less than ten seconds on her photo, but I spent hours replaying the morning in my head, imagining her years later looking at that picture and believing her mother had not tried hard enough.
It’s strange how small moments can lodge themselves in memory. Even now, when life is smooth, that picture sometimes drifts back. The difference is that I no longer treat it a…
Source https://tinybuddha.com/blog/what-happened-when-i-stopped-expecting-perfection-from-myself/

“There is no amount of self-improvement that can make up for a lack of self-acceptance.” ~Robert Holden
Six years ago, I forgot it was picture day at my daughter’s school. She left the house in a sweatshirt with a faint, unidentifiable stain and hair still bent from yesterday’s ponytail.
The photographer probably spent less than ten seconds on her photo, but I spent hours replaying the morning in my head, imagining her years later looking at that picture and believing her mother had not tried hard enough.
It’s strange how small moments can lodge themselves in memory. Even now, when life is smooth, that picture sometimes drifts back. The difference is that I no longer treat it a…