It is never too late to start
Source https://seniorplanet.org/articles-life-long-learning-life/
What new learning experiences do you enjoy to keep your brain healthy?
The post Lifelong Learning = Lifelong Benefits appeared first on Senior Planet from AARP.
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Source https://seniorplanet.org/articles-life-long-learning-life/
What new learning experiences do you enjoy to keep your brain healthy?
The post Lifelong Learning = Lifelong Benefits appeared first on Senior Planet from AARP.
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Source https://www.fightaging.org/archives/2025/09/fight-aging-newsletter-september-29th-2025/
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe to the newsletter,
please visit:
https://www.fightaging.org/newsletter/.
To unsubscribe, send email or reply to this email at newsletter@fightaging.org with “unsubscribe” in the subject or body.
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out more: https://www.fightaging.org/services/
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Source https://www.fightaging.org/archives/2025/09/fight-aging-newsletter-september-29th-2025/
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe to the newsletter,
please visit:
https://www.fightaging.org/newsletter/.
To unsubscribe, send email or reply to this email at newsletter@fightaging.org with “unsubscribe” in the subject or body.
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out more: https://www.fightaging.org/services/
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Reprogramming involves exposing cells to the Yamanaka factors, a set of transcription factors that are involved in the conversion of adult cells into embryonic stem cells in the earliest stages of embryogenesis. In addition to converting an adult somatic cell into a pluripotent stem cell, Yamaka factor expression also rejuvenates epigenetic control over nuclear DNA structure and gene expression and <a href="htt…
Reprogramming involves exposing cells to the Yamanaka factors, a set of transcription factors that are involved in the conversion of adult cells into embryonic stem cells in the earliest stages of embryogenesis. In addition to converting an adult somatic cell into a pluripotent stem cell, Yamaka factor expression also rejuvenates epigenetic control over nuclear DNA structure and gene expression and <a href="htt…
Regular exercise is demonstrated to improve many aspects of health in a dose-dependent fashion. Aerobic exercise and resistance exercise have overlapping but subtly different effects, and are often studied distinctly. Program of resistance exercise have been demonstrated to reduce mortality in older individuals, and more generally the view of “use it or lose it” is supported by the scientific literature. Exercise produces benefits, and a sedentary life is harmful to long-term health. Here, researchers demonstrate that the benefits of exercise in older individuals include improved peripheral nerve function.
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Regular exercise is demonstrated to improve many aspects of health in a dose-dependent fashion. Aerobic exercise and resistance exercise have overlapping but subtly different effects, and are often studied distinctly. Program of resistance exercise have been demonstrated to reduce mortality in older individuals, and more generally the view of “use it or lose it” is supported by the scientific literature. Exercise produces benefits, and a sedentary life is harmful to long-term health. Here, researchers demonstrate that the benefits of exercise in older individuals include improved peripheral nerve function.
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Mining human epidemiological data can only produce correlations. Mendelian randomization is a way to add data on genetic variants known to affect disease status into the mix so as to add some support for causation. The result isn’t a determination of causation, but in the best case is supportive of that conclusion. Physical frailty is well known to correlate with neurodegeneration, and a range of reasonable hypotheses exist to explain why this is the case. Both emerge from chronic inflammation and other underlying dysfunctions of aging, for example. Or frailty involves significant dysfunction in the <a href="https://en.wiki…
Mining human epidemiological data can only produce correlations. Mendelian randomization is a way to add data on genetic variants known to affect disease status into the mix so as to add some support for causation. The result isn’t a determination of causation, but in the best case is supportive of that conclusion. Physical frailty is well known to correlate with neurodegeneration, and a range of reasonable hypotheses exist to explain why this is the case. Both emerge from chronic inflammation and other underlying dysfunctions of aging, for example. Or frailty involves significant dysfunction in the <a href="https://en.wiki…
Source https://tinybuddha.com/blog/the-truth-about-my-inner-critic-it-was-trauma-talking/
“I will not let the bullies and critics of my early life win by joining and agreeing with them.” ~Pete Walker
For most of my life, there was a voice in my head that narrated everything I did, and it was kind of an a**hole.
You know the one. That voice that jumps in before you even finish a thought:
“Don’t say that. You’ll sound stupid.”
“Why would anyone care what you think?”
“You’re too much. You’re not enough. You’re a mess.”
No matter what I did, the critic had notes. Brutal ones. And the worst part? I believed every word. I didn’t know it was a critic. I thought I just ha…
Source https://tinybuddha.com/blog/the-truth-about-my-inner-critic-it-was-trauma-talking/
“I will not let the bullies and critics of my early life win by joining and agreeing with them.” ~Pete Walker
For most of my life, there was a voice in my head that narrated everything I did, and it was kind of an a**hole.
You know the one. That voice that jumps in before you even finish a thought:
“Don’t say that. You’ll sound stupid.”
“Why would anyone care what you think?”
“You’re too much. You’re not enough. You’re a mess.”
No matter what I did, the critic had notes. Brutal ones. And the worst part? I believed every word. I didn’t know it was a critic. I thought I just ha…
Source https://www.fightaging.org/archives/2025/09/betaine-as-an-exercise-mimetic/
Exercise has been shown to induce the synthesis of the metabolite betaine (trimethylglycine) in the kidneys. Separately, delivery of betaine was developed as a therapy for the rare disease homocystinuria due to its ability to blunt the harmful buildup of homocysteine in that condition. Here, researchers briefly review recent developments in the understanding of the ability of additional betaine delivered as a therapy to act as an exercise mimetic, triggering some of the beneficial metabolic responses to exercise.
Recently, researchers identified the <a href="https:/…
Source https://www.fightaging.org/archives/2025/09/betaine-as-an-exercise-mimetic/
Exercise has been shown to induce the synthesis of the metabolite betaine (trimethylglycine) in the kidneys. Separately, delivery of betaine was developed as a therapy for the rare disease homocystinuria due to its ability to blunt the harmful buildup of homocysteine in that condition. Here, researchers briefly review recent developments in the understanding of the ability of additional betaine delivered as a therapy to act as an exercise mimetic, triggering some of the beneficial metabolic responses to exercise.
Recently, researchers identified the <a href="https:/…
Source https://www.fightaging.org/archives/2025/09/reviewing-the-role-of-mtor-in-aging/
The mechanistic (or mammalian) target of rapamycin (mTOR) is a well studied portion of cellular biochemistry. The activity of mTOR and downstream consequences of that activity form one portion of a broad regulatory system that reacts to nutrient availability in order to change growth and stress responses in cells. Inhibition of mTOR is a necessary part of the beneficial response to fasting and calorie restriction, in which an increase in the activity of cell maintenance processes acts to improve health and slow the progression of aging. Animal studies robustly demonstrate extended lifespan in response to mTOR inhibition. In recent years a number of pr…
Source https://www.fightaging.org/archives/2025/09/reviewing-the-role-of-mtor-in-aging/
The mechanistic (or mammalian) target of rapamycin (mTOR) is a well studied portion of cellular biochemistry. The activity of mTOR and downstream consequences of that activity form one portion of a broad regulatory system that reacts to nutrient availability in order to change growth and stress responses in cells. Inhibition of mTOR is a necessary part of the beneficial response to fasting and calorie restriction, in which an increase in the activity of cell maintenance processes acts to improve health and slow the progression of aging. Animal studies robustly demonstrate extended lifespan in response to mTOR inhibition. In recent years a number of pr…
Source https://www.fightaging.org/archives/2025/09/valine-restriction-extends-life-span-in-male-mice-only/
Dietary protein refers to the intake of the nine essential amino acids that cannot be synthesized by our biochemistry: valine, isoleucine, leucine, methionine, phenylalanine, tryptophan, threonine, histidine, and lysine. The single value for “protein” that regulators such as the FDA required to be provided on food packaging is d…
Source https://www.fightaging.org/archives/2025/09/valine-restriction-extends-life-span-in-male-mice-only/
Dietary protein refers to the intake of the nine essential amino acids that cannot be synthesized by our biochemistry: valine, isoleucine, leucine, methionine, phenylalanine, tryptophan, threonine, histidine, and lysine. The single value for “protein” that regulators such as the FDA required to be provided on food packaging is d…
Source https://www.theminimalists.com/adtax/
The Minimalists discuss a secret tax being paid by those who can’t afford to opt out.
Do you think advertisements a tax on the poor? Let us know in the YouTube comments.
The post Advertisements Are a Tax on the Poor appeared first on The Minimalists.
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Source https://www.theminimalists.com/adtax/
The Minimalists discuss a secret tax being paid by those who can’t afford to opt out.
Do you think advertisements a tax on the poor? Let us know in the YouTube comments.
The post Advertisements Are a Tax on the Poor appeared first on The Minimalists.
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