Gero is one of a number of longevity industry biotech companies that put a strong focus on computational analysis of data to steer small molecule drug development and repurposing efforts. One of the interesting themes in their papers and presentations is the decomposition of signatures of aging into different distinct components, both in mice and in humans. When one can identify different overlapping trends in age-related changes in omics data, there is something to be said in that about the way in which aging progresses. The usual challenges apply, however, in that it is difficult to take this sort of analysis and link it back to fundamental mechanisms of aging. The research community as …
An Example of the Decomposition of Signatures of Aging into Multiple Distinct Trends
Gero is one of a number of longevity industry biotech companies that put a strong focus on computational analysis of data to steer small molecule drug development and repurposing efforts. One of the interesting themes in their papers and presentations is the decomposition of signatures of aging into different distinct components, both in mice and in humans. When one can identify different overlapping trends in age-related changes in omics data, there is something to be said in that about the way in which aging progresses. The usual challenges apply, however, in that it is difficult to take this sort of analysis and link it back to fundamental mechanisms of aging. The research community as …