Bemoaning the Lack of Standardization in Animal Studies of Aging

Source https://www.fightaging.org/archives/2024/03/bemoaning-the-lack-of-standardization-in-animal-studies-of-aging/

It is fair to say that the diversity of academia brings downsides in addition to upsides. A monolithic culture tends to mean slow progress: too little is explored at the borders of what is known when one viewpoint prevails at the expense of all others. A diverse culture produces such a variety of standards that it becomes challenging to compare any two studies. The paper-length complaint here is outlines the problems facing any scientist who is engaged in an analysis of published animal study data on the topic of intervening to slow or reverse aging, with a particular focus on the harms produced by a diversity of strategies for scientific controls in life span studies.

The search for interventions to slow down and even reverse aging is a burgeoning field. The literature cites hundreds of supposedly beneficial pharmacological and genetic interventions in model organisms: mice, rats, flies…

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