Brain Cells Exhibit Maladaptive Changes in Response to an Aged Signaling Environment

Source https://www.fightaging.org/archives/2024/02/brain-cells-exhibit-maladaptive-changes-in-response-to-an-aged-signaling-environment/

How much of the declining function characteristic of aging is a matter of accumulated damage versus maladaptive responses to that damage? Damage to tissues alters the balance of molecules secreted by cells in those tissues, thereby changing the signaling environment both locally and throughout the body, causing other cells and tissues to react. Some of those reactions are harmful. The chronic inflammation of aging is a prominent example, the immune system serving as a broadcast network enabling dysfunction in one location in the body to contribute to harmful consequences everywhere else.

Aging brings about a myriad of degenerative processes throughout the body. A decrease in cognitive abilities is one of the hallmark <…

Source https://www.fightaging.org/archives/2024/02/brain-cells-exhibit-maladaptive-changes-in-response-to-an-aged-signaling-environment/

How much of the declining function characteristic of aging is a matter of accumulated damage versus maladaptive responses to that damage? Damage to tissues alters the balance of molecules secreted by cells in those tissues, thereby changing the signaling environment both locally and throughout the body, causing other cells and tissues to react. Some of those reactions are harmful. The chronic inflammation of aging is a prominent example, the immune system serving as a broadcast network enabling dysfunction in one location in the body to contribute to harmful consequences everywhere else.

Aging brings about a myriad of degenerative processes throughout the body. A decrease in cognitive abilities is one of the hallmark <…

What Do You Think?

comments

Translate »