Centenarians Exhibit Better Protein Quality Control

Source https://www.fightaging.org/archives/2023/02/centenarians-exhibit-better-protein-quality-control/

Researchers here note that a number of cellular quality control mechanisms exhibit better function in centenarians than in the average elderly population. It is thought that the various systems responsible for quality control of proteins, such as autophagy, decline in function with advancing age. Given this, it is perhaps to be expected that centenarians exhibit a slower reduction in this capacity than their peers. In order to become centenarians, these individuals must necessarily be less impacted by aging, less damaged, less dysfunctional.

We have shown before that at least one intracellular proteolytic system seems to be at least as abundant in the peripheral blood lymphocytes of centenarians as in the same cells of young individu…

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