Characterizing the Brains of People Who Retain Cognitive Function into Late Life

Source https://www.fightaging.org/archives/2023/07/characterizing-the-brains-of-people-who-retain-cognitive-function-into-late-life/

What distinguishes the brains and biochemistry of people who retain good cognitive function into late life? That question provokes studies such as the one noted here, in which researchers assess structural and biochemical differences between older people with good cognitive function versus those on the more usual declining trajectory. It remains a matter for hypothesis and discussion as to how exactly cognitive function is maintained in only some individuals, in apparent opposition to the mechanisms of aging and their effects on the integrity of the brain. Gathering data remains an important activity at this stage of research.

Some individuals, often designated as superagers, can reach late life with the memory function of individuals 30 years younger. Previous neuroimaging studi…

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