When culturing any type of cell, the culture media contents come to reflect the secreted molecules and extracellular vesicles of that cell type – what is called “conditioned media“. It is a snapshot of the communications produced by the cell type in its current state. First generation stem cell therapies, in which the transplanted cells die rather than integrate with tissues in any useful number, influence health via the effects of their secretions and vesicles on native cells. It is much easier to build therapies based on the contents of the media rather than it is to transplant the cells themselves, from the perspective of storage, readiness, consistency of production, and so forth, and so this is the direction that the clinical industry…
Conditioned Media from Mesenchymal Stem Cells as a Basis for Therapy
When culturing any type of cell, the culture media contents come to reflect the secreted molecules and extracellular vesicles of that cell type – what is called “conditioned media“. It is a snapshot of the communications produced by the cell type in its current state. First generation stem cell therapies, in which the transplanted cells die rather than integrate with tissues in any useful number, influence health via the effects of their secretions and vesicles on native cells. It is much easier to build therapies based on the contents of the media rather than it is to transplant the cells themselves, from the perspective of storage, readiness, consistency of production, and so forth, and so this is the direction that the clinical industry…