Source https://www.fightaging.org/archives/2023/12/exercise-beneficially-alters-polarization-of-microglia-in-the-brain/
Regular moderate exercise remains one of the most beneficial interventions when it comes to slowing the progression of degenerative aging, if balancing effect size against volume of supporting data. This isn’t where we’d like to be! Biotechnology is capable of so very much more, but progress is slow, and robust assessment of new therapies across large populations slower still. Exercise introduces sweeping changes in cellular biochemistry and the function of higher level systems in the body, which makes it an ongoing challenge for the research community to understand exactly how it produces benefits. As is usually the case, there is a disconnect between (a) the data that can be connected on cellular biochemistry and (b) an assessment of health parameters. Joining the dots between the high level and the low level is a sizable project with no end in sight.
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Source https://www.fightaging.org/archives/2023/12/exercise-beneficially-alters-polarization-of-microglia-in-the-brain/
Regular moderate exercise remains one of the most beneficial interventions when it comes to slowing the progression of degenerative aging, if balancing effect size against volume of supporting data. This isn’t where we’d like to be! Biotechnology is capable of so very much more, but progress is slow, and robust assessment of new therapies across large populations slower still. Exercise introduces sweeping changes in cellular biochemistry and the function of higher level systems in the body, which makes it an ongoing challenge for the research community to understand exactly how it produces benefits. As is usually the case, there is a disconnect between (a) the data that can be connected on cellular biochemistry and (b) an assessment of health parameters. Joining the dots between the high level and the low level is a sizable project with no end in sight.
…
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