High Variance in Individual Responses is Another Complexity in Attempting to Slow Aging via Metabolic Manipulation

Source https://www.fightaging.org/archives/2025/12/high-variance-in-individual-responses-is-another-complexity-in-attempting-to-slow-aging-via-metabolic-manipulation/

Evolution produces species that exhibit stochastic metabolic variation from individual to individual. Any species or subpopulation of a given species lacking this individual variation might be more successful in a specific ecological niche, but would vanish due to competition the moment that niche changed in any way. And change is a feature of the world we live in. Given a long enough time scale, everything shifts in character. The species we see today are the descendants of the survivors of change, that survival enabled by individual metabolic variation within the species.

This adds to the growing list of complexities faced by any group attempting to find…

Source https://www.fightaging.org/archives/2025/12/high-variance-in-individual-responses-is-another-complexity-in-attempting-to-slow-aging-via-metabolic-manipulation/

Evolution produces species that exhibit stochastic metabolic variation from individual to individual. Any species or subpopulation of a given species lacking this individual variation might be more successful in a specific ecological niche, but would vanish due to competition the moment that niche changed in any way. And change is a feature of the world we live in. Given a long enough time scale, everything shifts in character. The species we see today are the descendants of the survivors of change, that survival enabled by individual metabolic variation within the species.

This adds to the growing list of complexities faced by any group attempting to find…

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