KCC2 in Alzheimer's Disease

Source https://www.fightaging.org/archives/2023/10/kcc2-in-alzheimers-disease/

The challenge with most identified mechanisms of disease is that they are not close enough to root causes to be highly influential on the progression of the condition. Particularly in the case of neurodegenerative diseases such as Alzheimer’s disease, the condition is very complex, and there is much to be discovered about how dysfunction progresses. That doesn’t mean that any given aspect of that progression will prove to be useful enough to make the jump from improvements shown in animal models to a basis for therapy in humans. There are many discoveries in the history of Alzheimer’s research that have appeared to be as interesting as the work noted here.

Studies have shown that even before Alzheimer’s symptoms appear, brain activity is disrupted in people who go on to develop the disease. There is <a href="https://doi.org/…

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