Larger Volume White Matter Hyperintensities Correlate with Cognitive Decline

Source https://www.fightaging.org/archives/2025/03/larger-volume-white-matter-hyperintensities-correlate-with-cognitive-decline/

White matter hyperintensities are small volumes of damage and scarring in the white matter of the brain, named for the way they appear in MRI images of brain tissue. They can be caused by rupture of small blood vessels, but also by any other localized cause of cell death and inflammation. Greater numbers of white matter hyperintensitives are generally indicative of a higher risk of neurodegenerative conditions and cognitive decline. Interestingly, researchers here note that the correlation with cognitive decline only exists for larger white matter hyperintensities.

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