More on the MTBR-tau243 Blood Test for Alzheimer's Disease

Source https://www.fightaging.org/archives/2025/04/more-on-the-mtbr-tau243-blood-test-for-alzheimers-disease/

Alzheimer’s disease progresses from an early aggregation of amyloid-β in brain tissue and mild cognitive symptoms to a later and much more harmful combination of inflammation and tau aggregation in brain tissue. A few years ago, researchers reported that measuring a tau species known as MTBR-tau243 in blood could be used to assess the state of this progression of Alzheimer’s disease, and did so as accurately as more expensive brain imaging approaches. Here find an update on this approach to testing and its continued validation in patients at various stages of the progression of Alzheimer’s disease.

Source https://www.fightaging.org/archives/2025/04/more-on-the-mtbr-tau243-blood-test-for-alzheimers-disease/

Alzheimer’s disease progresses from an early aggregation of amyloid-β in brain tissue and mild cognitive symptoms to a later and much more harmful combination of inflammation and tau aggregation in brain tissue. A few years ago, researchers reported that measuring a tau species known as MTBR-tau243 in blood could be used to assess the state of this progression of Alzheimer’s disease, and did so as accurately as more expensive brain imaging approaches. Here find an update on this approach to testing and its continued validation in patients at various stages of the progression of Alzheimer’s disease.

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