One Measure of Brain Age May Be Insufficient

Source https://www.fightaging.org/archives/2025/06/one-measure-of-brain-age-may-be-insufficient/

The brain is a complex organ. In this era of aging clocks, a number of approaches have been developed to assess the biological age of the brain from neuroimaging and other data. Is one metric for brain age sufficient, however? Here researchers present evidence for different portions of the brain to undergo age-related change at different rates. The researchers correlate their novel imaging-based models of brain aging to measures of cognitive performance in their study population, which gives more weight to the work than would have been the case for modeling alone.

Brain age is a biological clock typically used to describe brain health with one number, but its relationship with established gradients of <a href="https://en.wikipedia…

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